ID K0Z589_9ACTO Unreviewed; 349 AA.
AC K0Z589;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase {ECO:0000313|EMBL:EJZ87319.1};
GN ORFNames=HMPREF9240_00668 {ECO:0000313|EMBL:EJZ87319.1};
OS Winkia neuii BV029A5.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Winkia.
OX NCBI_TaxID=888439 {ECO:0000313|EMBL:EJZ87319.1, ECO:0000313|Proteomes:UP000006075};
RN [1] {ECO:0000313|EMBL:EJZ87319.1, ECO:0000313|Proteomes:UP000006075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BVS029A5 {ECO:0000313|EMBL:EJZ87319.1,
RC ECO:0000313|Proteomes:UP000006075};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Saerens B., Vaneechoutte M.,
RA Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Larimer J., McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Actinomyces neuii subsp. anitratus BVS029A5.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJZ87319.1}.
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DR EMBL; AGWP01000004; EJZ87319.1; -; Genomic_DNA.
DR AlphaFoldDB; K0Z589; -.
DR PATRIC; fig|888439.3.peg.671; -.
DR eggNOG; COG0836; Bacteria.
DR HOGENOM; CLU_035527_0_1_11; -.
DR Proteomes; UP000006075; Unassembled WGS sequence.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0005976; P:polysaccharide metabolic process; IEA:InterPro.
DR InterPro; IPR001538; Man6P_isomerase-2_C.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR46390; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR PANTHER; PTHR46390:SF1; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR Pfam; PF01050; MannoseP_isomer; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF159283; Guanosine diphospho-D-mannose pyrophosphorylase/mannose-6-phosphate isomerase linker domain; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000313|EMBL:EJZ87319.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000313|EMBL:EJZ87319.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006075};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EJZ87319.1}.
FT DOMAIN 3..279
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
FT DOMAIN 312..346
FT /note="Mannose-6-phosphate isomerase type II C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01050"
SQ SEQUENCE 349 AA; 37101 MW; 534F127454CCF73F CRC64;
MRAIIPAGGA GTRLWPLSKR NRPKFLLDLA GTGQSLLADA VSRLDGAASV MVVTGSMHED
AVRAQLDSNV EVITELSPRD SMAAIGLAAA IVEARHGRSE VVGSFAADHV VADVSEFRRA
VEAAVRAAQQ GWICTIGIGP RFASTGFGYI APGEETDCEG TRKVREFVEK PSQQVASEYV
RNGYLWNGGM FVAQAGVLLD TLALNHPHLA RGLRQIAAAW DGPERDDVRE RVWPCLTKIA
IDHAVAEPAA ALGKVAVAPT APSMGWDDLG DFKSLAKVAP VVQVGRKAAE VEADEGVFVA
TDLDSSEMIA VLGLEDVVVV RTKDATLVAS SEKAQEIKKL VETLPADYR
//
