ID K1KEL7_9BURK Unreviewed; 814 AA.
AC K1KEL7;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=DmsA/YnfE family anaerobic dimethyl sulfoxide reductase, A subunit {ECO:0000313|EMBL:EKB30164.1};
GN ORFNames=HMPREF9465_02230 {ECO:0000313|EMBL:EKB30164.1};
OS Sutterella wadsworthensis 2_1_59BFAA.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sutterellaceae; Sutterella.
OX NCBI_TaxID=742823 {ECO:0000313|EMBL:EKB30164.1, ECO:0000313|Proteomes:UP000005835};
RN [1] {ECO:0000313|EMBL:EKB30164.1, ECO:0000313|Proteomes:UP000005835}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2_1_59BFAA {ECO:0000313|EMBL:EKB30164.1,
RC ECO:0000313|Proteomes:UP000005835};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Allen-Vercoe E., Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M.,
RA Haas B., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M.,
RA Chapman S.B., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., McCowen C., Montmayeur A., Murphy C., Neiman D.,
RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Sutterella wadsworthensis 2_1_59BFAA.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKB30164.1}.
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DR EMBL; ADMG01000052; EKB30164.1; -; Genomic_DNA.
DR RefSeq; WP_005437105.1; NZ_JH815521.1.
DR AlphaFoldDB; K1KEL7; -.
DR STRING; 742823.HMPREF9465_02230; -.
DR PATRIC; fig|742823.3.peg.2238; -.
DR eggNOG; COG0243; Bacteria.
DR HOGENOM; CLU_000422_13_3_4; -.
DR Proteomes; UP000005835; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0009389; F:dimethyl sulfoxide reductase activity; IEA:InterPro.
DR GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR CDD; cd02794; MopB_CT_DmsA-EC; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.12440; -; 2.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR011888; Anaer_DMSO_reductase.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR006655; Mopterin_OxRdtase_prok_CS.
DR InterPro; IPR006311; TAT_signal.
DR InterPro; IPR019546; TAT_signal_bac_arc.
DR NCBIfam; TIGR02166; dmsA_ynfE; 1.
DR NCBIfam; TIGR01409; TAT_signal_seq; 1.
DR PANTHER; PTHR43742:SF3; DIMETHYL SULFOXIDE REDUCTASE DMSA; 1.
DR PANTHER; PTHR43742; TRIMETHYLAMINE-N-OXIDE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00932; MOLYBDOPTERIN_PROK_3; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000005835};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..814
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003846889"
FT DOMAIN 37..103
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 814 AA; 90400 MW; 7A9AFEA2D13A9EE5 CRC64;
MLSRRHFLTN TAMLGSAAGF AATPLSSAVA AAVDDLETTT WSCCSINCGS RCLLRCVSKK
GRVIRIETDN TGDPEAGASA TSCPQVRACQ RGRSIRQRLY SEERLKFPMK RVGRRGEGKF
ERISWEQALD EIAARLKKTI AEHTNESIML MHGSGSYSLF NNRNCTFRFF NMIGGNIGWY
SDYSAACIQH AWPYLYGGFG YGGVRSTNDG AGSYMNQVKN AKLYVTFGNN PAVTRASGGG
QSWELYGALR EGKTRMVVID PICTDTLAGR DAEWVAIRPG TDAALCEGMA WVMINENLVD
QAFLDKYCVG YDEKTLPKSA PKGSDYKSYI LGQGPDKTAK TPLWASRITQ VPVETIERLA
REIATTKPVF ISQGWGPQRR MNGETQSTAI AMMALLTGQV GLPGTNSGAR EGDSYGIDMG
LPTGKNPIGK SFPIFLWPRA VKDAKGMTAL NAGVRGCDRL EHNIKFIWNT QGNTLVNQHG
GVNQIREILE DEKLVETIVV VDNQMTPSAR FADYVLPDTM NQEIDDMQGD AYAVGDYNYI
VACPKAADIL WEQKPNYWIM TEMAKRFGLE EKFTEGRTQK EWIRWGYEQT LAKAAKQPDP
IKLPGFDEFW AKGFVKYHMG RDSGIVLKAF REDPEKHPLK TPSGRIEIYS ERLAKIAETW
ELPKTKGQEI HPIPRFIATA EMLGQGDPLE QKYPLEVYGY HGAGRTHSTY HNVPWLRALH
PDELMINPID AEPRGIKTGD KVRVFNDRGS LVIPAFVTAR VIPHLVAMPQ GAWYRPDEKG
VDQGACFNVL TTLEATPLAK GNPSHTNLVQ VEKI
//
