ID K1PBE9_CRAGI Unreviewed; 328 AA.
AC K1PBE9;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Growth/differentiation factor 9 {ECO:0000313|EMBL:EKC21107.1};
GN ORFNames=CGI_10004609 {ECO:0000313|EMBL:EKC21107.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC21107.1};
RN [1] {ECO:0000313|EMBL:EKC21107.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC21107.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; JH819179; EKC21107.1; -; Genomic_DNA.
DR RefSeq; XP_011420182.1; XM_011421880.2.
DR AlphaFoldDB; K1PBE9; -.
DR GeneID; 105322967; -.
DR KEGG; crg:105322967; -.
DR HOGENOM; CLU_919048_0_0_1; -.
DR InParanoid; K1PBE9; -.
DR OMA; HENEMAT; -.
DR OrthoDB; 2968469at2759; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd13756; TGF_beta_BMPs_GDFs; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 187..328
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 328 AA; 38028 MW; 5A8160BC8C3E3DE6 CRC64;
MDYHFSFCVF YWVFFAVCLV KCWPLNHENE MATPSTKEVP VSEQILFRNF MDALDRLDYD
EYSDISFHPV KIVNGEFEFD SSEFQAGHDV TGVDLIMKLS TNNSCRFAWA GNDIKVELRG
RRINSFVLFD FDHLLVMERS SELIKIRLLP TPNCPLQNQP TNSFLVIYRN LSKGPVLQKL
QELRISRIKR DSNTLPPIFS KDTYKRKNKI KSSIKDPGCH LVPWTVDFTR LQWDTFIVAP
VRYEANACQR TSAKCLETQK CSLPSKKHSN YEYLRQIYST KLGVSPPGNS SCKPSRYRSV
IILIIEPKKG RVELRTLPNM RVVECECA
//
