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Database: UniProt
Entry: K1PKW0_CRAGI
LinkDB: K1PKW0_CRAGI
Original site: K1PKW0_CRAGI 
ID   K1PKW0_CRAGI            Unreviewed;      1056 AA.
AC   K1PKW0;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   20-DEC-2017, entry version 29.
DE   SubName: Full=Short transient receptor potential channel 6 {ECO:0000313|EMBL:EKC19479.1};
GN   ORFNames=CGI_10008451 {ECO:0000313|EMBL:EKC19479.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Bivalvia; Pteriomorphia;
OC   Ostreoida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC19479.1, ECO:0000313|Proteomes:UP000005408};
RN   [1] {ECO:0000313|EMBL:EKC19479.1, ECO:0000313|Proteomes:UP000005408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC19479.1};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W.H., Paps J.,
RA   Zhu Y., Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J.,
RA   Wen B., Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D.,
RA   Xu Z., Liu Y., Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B.,
RA   Cheng P., Jiang X., Li J., Fan D., Wang W., Fu W., Wang T., Wang B.,
RA   Zhang J., Peng Z., Li Y., Li N., Wang J., Chen M., He Y., Tan F.,
RA   Song X., Zheng Q., Huang R., Yang H., Du X., Chen L., Yang M.,
RA   Gaffney P.M., Wang S., Luo L., She Z., Ming Y., Huang W., Zhang S.,
RA   Huang B., Zhang Y., Qu T., Ni P., Miao G., Wang J., Wang Q.,
RA   Steinberg C.E.W., Wang H., Li N., Qian L., Zhang G., Li Y., Yang H.,
RA   Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
CC   -!- SIMILARITY: Belongs to the transient receptor (TC 1.A.4) family.
CC       {ECO:0000256|SAAS:SAAS00933551}.
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DR   EMBL; JH818927; EKC19479.1; -; Genomic_DNA.
DR   EnsemblMetazoa; EKC19479; EKC19479; CGI_10008451.
DR   InParanoid; K1PKW0; -.
DR   OMA; MTKSFEV; -.
DR   OrthoDB; EOG091G01FB; -.
DR   Proteomes; UP000005408; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR   CDD; cd00204; ANK; 1.
DR   Gene3D; 1.25.40.20; -; 2.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR004729; TRP_channel.
DR   InterPro; IPR013555; TRP_dom.
DR   InterPro; IPR002153; TRPC_channel.
DR   PANTHER; PTHR10117; PTHR10117; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08344; TRP_2; 1.
DR   PRINTS; PR01097; TRNSRECEPTRP.
DR   SMART; SM00248; ANK; 3.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   TIGRFAMs; TIGR00870; trp; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 2.
DR   PROSITE; PS50088; ANK_REPEAT; 2.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023,
KW   ECO:0000256|SAAS:SAAS00933366}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005408};
KW   Ion channel {ECO:0000256|SAAS:SAAS00931870};
KW   Ion transport {ECO:0000256|SAAS:SAAS00929079};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:EKC19479.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005408};
KW   Repeat {ECO:0000256|SAAS:SAAS00931009};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|SAAS:SAAS00927442}.
FT   TRANSMEM    362    386       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    402    421       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    610    632       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    691    712       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       62    129       ANK_REP_REGION. {ECO:0000259|PROSITE:
FT                                PS50297}.
FT   REPEAT       97    129       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   REPEAT      179    211       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   DOMAIN      179    211       ANK_REP_REGION. {ECO:0000259|PROSITE:
FT                                PS50297}.
FT   COILED      888    908       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1056 AA;  122788 MW;  7F73550290676B64 CRC64;
     MHSDWRQYKY CALKRCSSFP LTSRNNEVND GMPYKSHQNK KSLSRLTLSS EKSSNSKGPL
     SDLEEEFIFA AEFGDIPTVK RLLEEHPNFN VDFNDILGRT PLRLAVGNEH LEVVELLLDR
     SNAASIHEAL LQAISAGHEQ IAETILKHPK YKDVKRENKR FGETDYFFNT TSEDSPFSSD
     ITPLILAAER NQFEIVQLLL LRGETIRKPH HYYCNCQECS NKLVFDQLRL AKTRLNAYRG
     LASSAYISLS SNDPILTAFE LARELRCVAK VEKYYKSDYL ALADQLSEYV VRLLDKVRGH
     DELEKLLNKK KREPDDETYE QLSRLKLAIH YSEKKFVAHA SCQQKLVSIW YNDLRAMERS
     NWFFRSLMVF GVTSVYPLLA ILYIFAPHSK VGRFLQYPCI KFIGHAMSFV TFLIMILISS
     AEGTTDLSRM SSFPGPYRHY LWYKNHSRLT LPEDFVVRTC RPEVIQIGLS LWIIGMLWQE
     IKQVFSEGLY DYFDSLYNYL DVAVLTLYLS SFTLKYVCIW KVNVALQYFE AREPWEKLLV
     SDQTAAKKMY WIIADRFYWD SLDPHNIAEG LFAIANVISF TRVSYILPAN EMFGPMQISI
     ARMMTDIIKF LAIFLVILVA FMVGLHNLYW YYPKQVREKV EFMKNNITVR AEEAFGIPDK
     TVRTVFWSLF GRGDATIVEL DEFEHIFTQY VGYWIFGAYN WCSVIVLLNM LIAMMSRSFE
     LIQEDSDTEW KFARSKLYMD YIKSGATLPI PFNMIPTPKS VWKLCSKFSR CFCKGEAGEM
     RPHPGRIKDV ELYATSPTTT NSGWDDGHSA HQANGIKRFR ERMQTTNGFV RSDSEPNLFE
     EKLTYKRVMK RIVKRYIFDM QRENDSNDDF DEVKQDISSF RYEILNHLQS REDESQDCRE
     KINKMEQKMT HLIHQQTVLL NKLGQTNTAD VYQNGGHAND VHRSRDKSED DTGLAAPLLT
     ESAYSSLDEP SLEDELLQQL SMSRNQYLED IPEEEATSQR EDRRLKVRVR SDSQDTNTSP
     RLSRQQSLDD ENYSTDDIIV HVMNENDVKN AFDAKL
//
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