ID K1PTT8_CRAGI Unreviewed; 1441 AA.
AC K1PTT8;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Neurogenic locus notch-like protein 2 {ECO:0000313|EMBL:EKC27687.1};
GN ORFNames=CGI_10013841 {ECO:0000313|EMBL:EKC27687.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC27687.1};
RN [1] {ECO:0000313|EMBL:EKC27687.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC27687.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH817588; EKC27687.1; -; Genomic_DNA.
DR HOGENOM; CLU_251854_0_0_1; -.
DR InParanoid; K1PTT8; -.
DR OMA; NSATCIC; -.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 3.
DR Gene3D; 2.10.25.10; Laminin; 5.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR PANTHER; PTHR24033; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24033:SF151; PROTEIN EYES SHUT; 1.
DR Pfam; PF00008; EGF; 2.
DR SMART; SM00181; EGF; 8.
DR SMART; SM00179; EGF_CA; 3.
DR SUPFAM; SSF57196; EGF/Laminin; 6.
DR PROSITE; PS00022; EGF_1; 5.
DR PROSITE; PS01186; EGF_2; 5.
DR PROSITE; PS50026; EGF_3; 8.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 161..196
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 214..250
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 375..411
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 429..466
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 797..835
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1025..1063
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1180..1217
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1301..1339
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 186..195
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 240..249
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 401..410
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 456..465
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 806..823
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 825..834
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1034..1051
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1053..1062
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1207..1216
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1310..1327
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1329..1338
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1441 AA; 156677 MW; EBCBED374C6EE324 CRC64;
MPAKITVSWI PVGADLGKDI LCARVEDNEG FESINLHCFT ILIKPYAQHP QTPLQARPYF
VFFPQPGDIV FPEHSFCKFP IYAASSTKGG ITNISIQSTD APSAVVVSVI RPVNSTYGPG
AKMVEIQLKE PVGGVRKICF EASDADSSTV KCLFANVLKK EVDKCLNDPC GDHGICIDGD
TSSCNCTDGY TGEFCTSMKN GESRCYFVDV VKNIEGVCDP NPCENGGLCL HKDGMPFCIC
MTGYYGDNCT KGFEHKTQIL TDLAMPEKIM CHVKEKCDIS FSISTNGSSR LTTDERCIDV
VVENNKIQQT KGNSDFTHVF NLNTNFKAIG NNCTADVAIK PSSNHNSSDP YCFDVSFPSV
PGEKRCFNVT YKEPEKTLCV GFLCENGGFC ETKDLKATCK CPITTSGKNC QSSDGERRCF
KFFVNNETQG SSCEYISCLN SGYCEGDVQG NTSCVCMGGH TGPLCSLEGG SLPTNHIQYS
SPDPEASPKF IDTAIPNILP CKVNTECGIS LFLKGNPYKR NKEDELCFKI NVTDVGLHAK
VTPIIPDARV LSTYLLGNHC LADVVVRTHK EDLNKSVCVQ IDGTTISSDR EKRCVTITVS
KHVLAKPTPI PREKNNTNTS NLLPKFVDSV LPKEIKCTVS RDCIITIPVH GFPMNQSTLL
FGHFDKGVVP GPIITENITD PTNQTLAYFH LKATNAENKY VCVQSSNLQI NTDELCVKIV
VANKTDIKNM VSSTITKVHS FTSDHPIGPN NLCHVDVTFK PEVAGNHTLC IQAKDNGHDG
DERCYAVNVV TKTNITYGGP CQSHPCYNKG HCEADPTAKT AICLCPVGLS DSNCQKIGPV
KPTQSTTSPT VITLTCSKRI HRYCDSKCNT MPNKLNMLDT PHHFWTTRRY IITEPTIPDQ
SSVNVVPHQS VVTSGTVVLS TEQTTFNQSL CVTDVATVAR PVGQKTICLE TSSTDKRCID
TIAQFHMTSI SSGNKHVCFQ TSDFTTSPQK LQHLQCLMEL SFNVYLVKGA VTFLCTQNQC
KVPANGGPCQ QKHCYNNGKC EADPVSNSAT CICPIGYPDE NCLSNVSLSP PIPGSTVLPI
TKPIFTDTAI PDIIQCPSGS TCGVPLIIRG EPGKILVPML SPLSPGMAVL TTEETQFDPN
LCVTDIATIV KPSETKKLCV DVTGSSYKRC IIVNSVRNMT KSSCNSNPCY GNGYCKSSDK
NGFICICKLG FKGDHCENSG ISEIRRYNAA KRDHVSIERR LFNSISSEWE SHQSKFNSVW
TCRQRNVDEV CLKVVVHNET QPAVSTPSPN SPEITHPSFP NGGPCQEMHC QNEGKCEADP
SSQSSTCICP IGFNDAKCES NVNVLPTAPG PTPQPSTKPI FTDTAIPDVI QCPAGAKCNI
PLIIKGKSGK IPNVDSDNSL VSQPIETVHY PGKKNNTYQT NIQIIGSSGL HTVCSHIDDK
G
//
