ID K1QFQ0_CRAGI Unreviewed; 594 AA.
AC K1QFQ0;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Homeobox protein Hox-A2 {ECO:0000313|EMBL:EKC32708.1};
GN ORFNames=CGI_10024086 {ECO:0000313|EMBL:EKC32708.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC32708.1};
RN [1] {ECO:0000313|EMBL:EKC32708.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC32708.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
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DR EMBL; JH816167; EKC32708.1; -; Genomic_DNA.
DR AlphaFoldDB; K1QFQ0; -.
DR HOGENOM; CLU_459473_0_0_1; -.
DR InParanoid; K1QFQ0; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR PANTHER; PTHR45664:SF12; PANCREAS_DUODENUM HOMEOBOX PROTEIN 1; 1.
DR PANTHER; PTHR45664; PROTEIN ZERKNUELLT 1-RELATED; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682}.
FT DNA_BIND 60..119
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
SQ SEQUENCE 594 AA; 66279 MW; FF126F571D6EF26A CRC64;
MQNRSMFAHV WDTEVVIMWD LDSTMSSDFP SPQPAITNNQ PPQPQEPRSN SSSHSNGGGT
RRLRTAYTNT QLLELEKEFH FNKYLCRPRR IEIAASLDLT ERQVKVWFQN RRMKYKRQTQ
SQRQKAESDF KSMSYDGNLD SPMSSDESCD RMERRESYDS CNDNRDDLCN STDKSGQEAM
NTGLECDNEK HRRPHSADRL MVKPEGSDVV ELTVLSGRER FSDARRSNMS DMSDPQQRSP
IGSVQSLHSP MSSASNMLPT PPVASSPLAS PDVRSVDFAD KIINDSELIS KSSHNNSSAN
GGGLVSKNLC VKMTEVEGAC MDTLNSNKTS HSTMRSPECT SPGAKDSGHI VHSNNTPVME
GNNVFQSYNG HDSNHSSYQS SYPGSMGYLQ KQTAAFNNCS AENYYDNPGD SPNRIGRFGG
NGFNSWNYDG ANPLNSQNAN YHNNRIGFGM NGNHLYSPNF SRVNNFNPRE AEMPSLPSRH
FNSRYMTKSS AYPQQMPGID QHSSTSLYGS NYMESFSEGV NQVVNSPICQ SPSRPTPRPG
DSISRTQAGL AIEPHYTSDQ YPLAHSYNEA GPSGDFTSIF SEYFNSQQPE YQAI
//
