ID K1QMS0_CRAGI Unreviewed; 1239 AA.
AC K1QMS0;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Transient receptor potential cation channel subfamily A member 1 {ECO:0000313|EMBL:EKC30140.1};
GN ORFNames=CGI_10021964 {ECO:0000313|EMBL:EKC30140.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC30140.1};
RN [1] {ECO:0000313|EMBL:EKC30140.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC30140.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
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DR EMBL; JH818702; EKC30140.1; -; Genomic_DNA.
DR AlphaFoldDB; K1QMS0; -.
DR HOGENOM; CLU_006750_0_0_1; -.
DR InParanoid; K1QMS0; -.
DR OMA; HWATEKN; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 5.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR PANTHER; PTHR47143; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS; 1.
DR PANTHER; PTHR47143:SF3; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS; 1.
DR Pfam; PF12796; Ank_2; 4.
DR Pfam; PF13637; Ank_4; 2.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 13.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR PROSITE; PS50297; ANK_REP_REGION; 10.
DR PROSITE; PS50088; ANK_REPEAT; 11.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000313|EMBL:EKC30140.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 864..1071
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
SQ SEQUENCE 1239 AA; 138821 MW; DEF50DCAC54158AA CRC64;
MTETVAPDSP NNSLVELVSD PRAKNRKLKW FSKKRLMGKR VFSEIYKDTG MDGMRGSTRD
GTVIPQGTVC FMSENPYRIC KTNTMSTEKR RKFALSGIFR RRRTDKPTEE VGIDLLHPVD
DGDPTKSIPS NAGGSGDEDI GKVAAAGNVT ELQQILNNDP SRINAQDTRG WSPTHHAASR
GFTDVISYIS SQGGDINLQD REGNTPLHVA VEKGQQTAIE TLIGLGADTS ILNFAKMAPV
HLAVDLGLLE PLRTILIKDK TSAILPGETG ATPLHYCAYK DRDECAKLLL EHGAKPCKSC
DDGFYPIHAA ATRASDKTLE VLIKHVERLG YTREVVLSFT DKYNNTPLHS AVSSGDPEAV
RVCLNAGAAL DVQQEDKSTA LHFACAQGGL SIIHMMRQLQ PEKFMTASKK TDILKMTPLH
RAALFNHVNV VKFLIDEGVE VNAVDSQKRT PLLLAASKGA WKTVHLLLES GADISLKDNK
NRNFLHLAIK YGGKLNQFGV QSIKHFKNLL NEKDDYGCTP LHYASREGYL VALDDLIELG
AIVNPKNKDK QSPLHFAARY GRYNTCRRLL DSKLGPNIIN ESDCDGFTAL HLAALNGNVK
IINLLMQKGA RVTRAHDDNS PIHMAALNGY TKCIRALLGV HANILDVKNK NGDTALHLAS
RAGQPKVVDL LLSLGAKISL NIEDKSFMDI AIENRKAAVA LTSVKHERWS EILHTCSKTF
GCPMHGLIQH LPDVCMTVLD RCVTNVGNPH KKDYYIEYNF EYLQCPVRFV REANKNGGDI
QPMFALNMMV RHGRVECLSH KLCRTYLTMK WRAYGMWVHS VNLVLYIVYL ALLTLLATKD
FTSHTPLPNN STLNSTQITG TKSDEMTTWY RMITGLVFVL TSINILKELV QMVQQRLRYF
LDPNNLVEWV LYVSTAVFIA PVLFNDSDCL NMEAGAVAVF LAWFNCLLFL QRFDVFGIYV
VMFLEILATL FQALCVFSIL LVAFGLAFSI LLRHEDSHAY STPLMSIVRA TVMMLELDYM
SSFNEPYFDD KPSTLPYPSL TVFFMLLFVL LMPILLVNLL IGLAVGDIES VLRNATLKRL
AMQVELHTEL ERRLPAKLLE KVDKIKHKEY PNKCGKYVRV FKNLMEKDAD SSSVCGGEEA
SYVKTELFKQ KTRLKELSVN MERNYDMLKL IVQKMEIETE ADNHDEGFHT SHSLDDVINP
TCSKWNSDVL RKNLIRQNAV ISKWKEHSQH SNIQSTFDC
//
