ID K1R0V4_CRAGI Unreviewed; 611 AA.
AC K1R0V4;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 13-SEP-2023, entry version 38.
DE SubName: Full=Toll-like receptor 2 type-1 {ECO:0000313|EMBL:EKC34755.1};
GN ORFNames=CGI_10021741 {ECO:0000313|EMBL:EKC34755.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC34755.1};
RN [1] {ECO:0000313|EMBL:EKC34755.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC34755.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
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DR EMBL; JH823219; EKC34755.1; -; Genomic_DNA.
DR AlphaFoldDB; K1R0V4; -.
DR HOGENOM; CLU_447089_0_0_1; -.
DR InParanoid; K1R0V4; -.
DR OMA; DITESCK; -.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:0002224; P:toll-like receptor signaling pathway; IEA:InterPro.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR017241; Toll-like_receptor.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR24365:SF541; MSTPROX-RELATED; 1.
DR PANTHER; PTHR24365; TOLL-LIKE RECEPTOR; 1.
DR Pfam; PF01582; TIR; 1.
DR SMART; SM00369; LRR_TYP; 3.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Receptor {ECO:0000313|EMBL:EKC34755.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ SEQUENCE 611 AA; 71792 MW; 46B5A0CEAA8A934F CRC64;
MDFRYHVYCD VTEDLFCSFP VISREIVLNF GGHCDVIVAL RSLKCLQNRK VESISLSSNK
KRFESGILIL NNWTMEYLAN ICVKNLSLGY NSIVFLNATL YKTTLWKCLE KFDFHGNNMH
VIDVSTLMSL LTLPKIRILN LCCNDPPTSK TKYRDDPFQI QKHRFIYVNI TLSKNLKLLD
ISDNYFHNTN GWNLRFVLIG EELEELYLQK TNFPLHTITK LNFPNLIKLN LSENSFRQVH
SDMFQGVRNL HHLYVLDVGL NNTAHSISNS LFKNLKNLLT LDFSKNGLAF LPSLLLMDQK
HSLTEIRLDH NRFSAVPSVL TELKELKTLY VRFNLISKFS RNDQRLFQSL SNLSIYIEGN
PITCACTGVQ SLKWMKAHQN IFYDLNKVLC VESKIPIVQL LYEKEWRKFE LNCQTDDWLV
FSVCLLFFTI VSLTIIASVK RYRVHLEYVI LRLKNRWKGV HQKSNEDMFL YDVYISYNDA
DCSWVIETLY PKLEVLNIKT WFGDKDSIPG RWKSEEIVGC INESRKVMFI MSESFLERGW
HSYAVQMAIT HAFHNQRQRS IVLIIKDGLP LDRLPNEIKN IWWCIEHFRW PENEQHDEMI
FSTLSKILKP K
//
