ID K1R9J7_CRAGI Unreviewed; 2307 AA.
AC K1R9J7;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Fibrillin-3 {ECO:0000313|EMBL:EKC40349.1};
GN ORFNames=CGI_10018675 {ECO:0000313|EMBL:EKC40349.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC40349.1};
RN [1] {ECO:0000313|EMBL:EKC40349.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC40349.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH822105; EKC40349.1; -; Genomic_DNA.
DR HOGENOM; CLU_230101_0_0_1; -.
DR InParanoid; K1R9J7; -.
DR OMA; CINENEC; -.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 9.
DR Gene3D; 2.10.25.10; Laminin; 23.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 2.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR003886; NIDO_dom.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR InterPro; IPR001846; VWF_type-D.
DR PANTHER; PTHR24034; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24034:SF166; VACUOLAR-SORTING RECEPTOR 1; 1.
DR Pfam; PF12662; cEGF; 4.
DR Pfam; PF07645; EGF_CA; 10.
DR Pfam; PF12661; hEGF; 1.
DR Pfam; PF06119; NIDO; 1.
DR Pfam; PF00090; TSP_1; 2.
DR SMART; SM00181; EGF; 23.
DR SMART; SM00179; EGF_CA; 19.
DR SMART; SM00539; NIDO; 1.
DR SMART; SM00209; TSP1; 2.
DR SMART; SM00216; VWD; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 4.
DR SUPFAM; SSF57184; Growth factor receptor domain; 6.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 14.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS01186; EGF_2; 15.
DR PROSITE; PS50026; EGF_3; 17.
DR PROSITE; PS01187; EGF_CA; 7.
DR PROSITE; PS50092; TSP1; 2.
DR PROSITE; PS51233; VWFD; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022530}.
FT DISULFID 189..198
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 371..388
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1212..1221
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1404..1414
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 2307 AA; 247109 MW; EDF735381992F918 CRC64;
MSTEITASSS SQLENLSTLS PTSANTPLST EIISSTSTQS GNPSSKTSTV FQTSQVTSPH
TPPVTTTQAS YTQTTPLSSI HTPPVTATTE HKSNTTNNPL EISSPSNVNS TDSTTTTTTK
AVEPTTTTIK VVETTTTTST SAAPTTTVTT TTTTIPTTTT EDKCASVVCQ NNGNCVQSPG
SPTGYTCQCN QNYTGDTCQF AVASYTQWGE WGYCDQNCKG GVKTRNRTCS DATGANRGQD
CGPDLQETIE CENLPACVVT TDPCASVINP CLTDGVNHTC LVKSDGSFRC LCLSGYVNDA
NNKYCINENE CTRTNNDCND VNTSGLKVGV ASCKDTVGNY SCVCSSGFTY DSSARTCTDV
NECSSTSTNN CDVTDRATCT NTPGSFTCAC KPKFQGAGTA GTCKEIRLLP HTGHTKLANS
DGFSTYFFPK YAVPFGSHLY PSFYFTRSGL LLFTTVTSEK VGIGQRKSFT NPAKFTIDAT
FQEKAAFAPW WSNMMISSGA SADNGVYYKE YSADVTSENT FMVDKAAEIA GSLSVSGFSP
KYMIVITWYK MEQNKSPATP SQTVTFQLIL VTDFLHTLVK VAYEDREMKW DVLNSVGNYP
VRIGLLKQGE TSEEYSYSYL DLLSNAANKS KIERIDEVTF TNPSSIGRSF YRLSETSPIS
HPGIQCLNWI TSDDADTSNP VVTSEVTQCP PSLLQKTDSL VQYTKAEIPS SVECYGKRSA
LSTTFTDPRT MRCCFDKANK GLILDHVLAN GFNTYMRHSG QDQEKVHEAY EWCCNASNRY
ASRADVCQNF LSRRPVCTSD DFIASGAGGA LGDPHLTTLD GLSFTFNGHG EFILLNASDV
QVQGRFTPFM KDGKKQPATY ISSIVGKQTG SDKVEIRLNT TKDGAEILKN GVVLDPLDLT
NDQDWTKVSV SKSTDASSVH TWKMIFSNGL TAGVQLKNEM FQLVIESAAL YKSNFQGLLG
NFNDNPADDF TAPNGSVTPS TSNEEAIYNY GKVWQNSEAT SLFTYDGKTT GDNDNWGSHV
DADYQPVFFN PNLTAMFTDD SKRTTAISTC NNGATTDDNP TLRRECYFDF KVTDNADLAS
ATSDTKAALD ETKSTLANYP PEIANGNVTI EVSVGATYTL HLTATDKNAG DIIFFLINDD
APSGLVVTND THNLTWTNIA DLETAKIQVT VSDGKAQSLW TPKIEYCKCQ NGGGCDFSVS
SSDQFLLVPC VCVTGYTGPF CERDEDGCAD NPCWPGVDCT DVLARDLSTT PAGFKCGSCP
THLEGDGISC TDKDECVKNS PPPCSHNCTN IEFGFTCSCA EGYVLGADGK TCTDKDECTT
NADKCNDVTT TCLNSVGGYS CPCKTGYQRE TTYTCTDVDE CTNSSNPCPA NSRCQNSVGS
YDCVCNYGYS KNTQSNTCEE INECAGTNNC AQRCVDGIGT YTCACNTGYK LNTTDLVSCL
PENECSTEEK NTCDGGSETA SCAVSNGQVY CGCPSGYALN ASKYCIDIDE CATNVDTCVD
SSSTCVNTPG AFRCDCKTGF NKLSDFICAD KDECTLNTDT CVAPATCQNN DGSFTCSCPV
GYTKGSDGNS CTDIDECASA ATHSCDKEHG RCTNTAGSYT CSCNSGFTGD GYTCADKNEC
ASGSTNQCEQ TCINNIGSYT CSCFRGYTLN ADGRRCNDIN ECSESAANGC YDNNHCENTI
GGYTCSCPTN FELKGDAKFQ CASNHGCSHT CGKIGEVDTC SCPAGYELDG TKKNCVDIDE
CSSDALHRCL AANNVSCSNT VGSYVCNCVS SQYVKSQDIV CVDADECTLG TANCPSNSLC
VNRDQGFDCN CFSGYTKVGD TCQDNNECDG SNDCNSALGT CTNTPGAYKC ACKAGYTGDG
RTCQDVDECS ENTHNCDSRQ ERRNCTNTEG SFTCGCLEGY TLASDDRTCN DVDECSTSSH
ECEHTCVNKN GGYDCSCQLG YRLEADQRTC TDINECTGSP CHSTHSACQN TVGSYTCSCT
DGYILGPNNV CVDRDGGLSD WSAWGTCSQT CGSGTQTRTR ACNKPTREGS GRDCTGSLSE
SQACNTNLCP PTEDEQTYGV IIQYKGVTAD HFTVEVKAKF TSKIATEINK YCNTDNTNLR
QCCNSQSTYA PSISSIKSFT KAEQIAIGDG YPRDVNGGTQ ILVVVKGDKS NALCSATSSR
RRRSITLSNL EIAIPQSVLQ QIMANATIQD EIIVQLAAAI KEHTNATLSI TAGEIMLVTA
PTSTPTESNT SQAWVVPVAV VGAILGVILV IVIVLLIVKM NKKNKINPDD RHANPLNDPS
HPANNPPQPQ PVNQGSNSPQ GDRAPLT
//
