ID   K1RD67_CRAGI            Unreviewed;       742 AA.
AC   K1RD67;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Prominin-1-A {ECO:0000313|EMBL:EKC41599.1};
GN   ORFNames=CGI_10025055 {ECO:0000313|EMBL:EKC41599.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC41599.1};
RN   [1] {ECO:0000313|EMBL:EKC41599.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC41599.1};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA   Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA   Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA   Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA   Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA   Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA   Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA   Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA   Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA   Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the prominin family.
CC       {ECO:0000256|ARBA:ARBA00006058}.
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DR   EMBL; JH818738; EKC41599.1; -; Genomic_DNA.
DR   AlphaFoldDB; K1RD67; -.
DR   HOGENOM; CLU_008293_1_1_1; -.
DR   InParanoid; K1RD67; -.
DR   OMA; CGNTKER; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008795; Prominin.
DR   PANTHER; PTHR22730; PROMININ PROM PROTEIN; 1.
DR   PANTHER; PTHR22730:SF1; PROMININ-LIKE PROTEIN; 1.
DR   Pfam; PF05478; Prominin; 3.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
SQ   SEQUENCE   742 AA;  81458 MW;  F4D7B877FA812330 CRC64;
     MEGMKLRVWL YLSVWGALCV WMVVGANGGF TLPPGPPSPD YKADDVKYED GGMGPLYNFA
     RKFINMCLSD IKDVIEVIKD AIKGKIGSNV QDILQMVRSN FLGFSISVVV GLLFIVIFPI
     VGCCFCCCRV ACKACCAQPD EEDPSVSCKK AIYGTILFVI VAFTAAGNIC VYVSNDRISL
     ALTEIVDNVD KNLDDIKLFM EHSSKQVDSI KTNFQTAKTE LDNHLDATKL SEALQKKAIS
     LLTGGAVDHL QTDIDDVIST VTNVNTAMND FQAACPPAVC SSPISPPNLQ TLPSIDISNQ
     VAISAAKTQL NSADTKIGNL VDNTKDAIQK VAGDVVNIKD TKTMVKNQKD FITPYDKYRW
     YAGIGCGGIV SLILALYCCG ICCGCCGGRS VNDPLEKGCV SNCAGRLMIG SLVFIFVFCP
     LLMLITTLMY IPGAIIERYV CQPFTDPNLE FLDELMDSFE MNFDNIVKHE PGHEMSLKSF
     LGNCKNNMAI YKALDLEHLT LFSFKFSDLE NEVQNIMNHM NTGMGTMLND KTAFGSANLL
     PAGLVTNLDG IKNTMSSLDL TSLNNATAVD DVKHQLNAAT TNMQSNGMTN IAQSFVNDTV
     NIIDVYFKDV KGKLHNEIGQ CQPLWNLYNS IIKISLCQYI VDAFNGFWFS IGWCIFFLLP
     GAVVGTKLSN FLRDVKYVYD NNHDAESGKS KRTKNLPTAN ICIGDHSVIS EGVLEPHYSS
     NKLRRPLTTA RGHTRVNCLM RK
//