ID K1RDT2_CRAGI Unreviewed; 665 AA.
AC K1RDT2;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Cilia- and flagella-associated protein 52 {ECO:0000256|ARBA:ARBA00029552};
GN ORFNames=CGI_10026256 {ECO:0000313|EMBL:EKC32266.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC32266.1};
RN [1] {ECO:0000313|EMBL:EKC32266.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC32266.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
RN [2] {ECO:0000313|EnsemblMetazoa:G3365.1:cds}
RP IDENTIFICATION.
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EnsemblMetazoa:G3365.1:cds};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC {ECO:0000256|ARBA:ARBA00004230}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the CFAP52 family.
CC {ECO:0000256|ARBA:ARBA00029456}.
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DR EMBL; JH818863; EKC32266.1; -; Genomic_DNA.
DR RefSeq; XP_011416101.1; XM_011417799.2.
DR EnsemblMetazoa; G3365.1; G3365.1:cds; G3365.
DR EnsemblMetazoa; G3365.2; G3365.2:cds; G3365.
DR EnsemblMetazoa; G3365.3; G3365.3:cds; G3365.
DR GeneID; 105320039; -.
DR KEGG; crg:105320039; -.
DR HOGENOM; CLU_009244_2_0_1; -.
DR OMA; YFPTGVQ; -.
DR OrthoDB; 905838at2759; -.
DR Proteomes; UP000005408; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13720:SF14; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 52; 1.
DR PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR Pfam; PF00400; WD40; 7.
DR SMART; SM00320; WD40; 12.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Flagellum {ECO:0000256|ARBA:ARBA00022846};
KW Reference proteome {ECO:0000313|Proteomes:UP000005408};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 448..482
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 499..540
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 583..624
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 625..665
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 665 AA; 73787 MW; 761B18D82BAA66E6 CRC64;
MGDSPINVPR LELDSVIGFN GSVASGLKVH PGREHLIYPL GCTVVIENIA TQKQDFLWGH
TDNVSCVTVS PSGKYLASGQ VTHMGFKADV IIWDFESRQL YARLTLHKVK VEDLAFSPNE
LYLVSLGGQD DSCVVVWDIA KKEAICGHQA QVESAGITYC VAFSNRSDDV FVTGGDGTLR
VWELDRDNRK IRPTDVTMGQ LKRVVKCIQM ADNFQEPFFF CGTTTGDIIG VNMNTKFFQF
LGPEKEKFKS GVTCLSLIKS GQLLVGSGDG EVALVQFFNK VEKDSKNKKG KICFEKKRSW
RDCKTKKTCA ITSIALRGDG HQFYVGTANS QIYRFNFAEF NCEKSKDNAN QGAELIKTCH
SHEITDVVFP YGTGELIVTS QYEEIRIWQL KLKKEIRRQV VKNMTCNAVD LTRDGKTIIS
AWDDGKIRGY GFAAKDKSTS LVEKFLIEEA HSKGVTALAC TSDGLGIVSG GGEGQVRIWR
ISKSYDPRGK DTVSLVETMM EHKGRVSDIK ITRNDKECAS ASTDGTCIIW DLERRKRSQI
VFSNTLFQAV CYGAKECQII TGGTDRKVGY WECCDGKGIR ELEGSKSGSI NAMDVSPDQN
YFVTGGDDKL LKVWTYEDGE VIFVGIGHSA PIKKAKICPN QRYIVSVSAD GAILVWKFPQ
EPRIK
//
