ID K1RY73_CRAGI Unreviewed; 1787 AA.
AC K1RY73;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=CGI_10026970 {ECO:0000313|EMBL:EKC39961.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC39961.1};
RN [1] {ECO:0000313|EMBL:EKC39961.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC39961.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; JH816287; EKC39961.1; -; Genomic_DNA.
DR HOGENOM; CLU_000315_8_1_1; -.
DR InParanoid; K1RY73; -.
DR OMA; WVQIRDD; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18666; CD1_tandem_CHD1-2_like; 1.
DR CDD; cd18661; CD2_tandem_CHD1-2_like; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 2.40.50.40; -; 2.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR040793; CDH1_2_SANT_HL1.
DR InterPro; IPR025260; CHD1-like_C.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR023779; Chromodomain_CS.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45623:SF14; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR45623; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED; 1.
DR Pfam; PF18375; CDH1_2_SANT_HL1; 1.
DR Pfam; PF13907; CHD1-like_C; 1.
DR Pfam; PF00385; Chromo; 2.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00298; CHROMO; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01176; DUF4208; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00598; CHROMO_1; 1.
DR PROSITE; PS50013; CHROMO_2; 2.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000313|EMBL:EKC39961.1};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EKC39961.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ SEQUENCE 1787 AA; 202449 MW; 5F9FBFDAF7669CEB CRC64;
MADLAEIPSI EDPADFDSPL FGPLSNDKSP KAGSSNKENK DSIKKEIENN ASGSGSDSGN
SSGSSSDESD SESGSRSGSN SETSSSESDD SESNERSERK TASHLDDDSQ DTQSTNLSSK
RGRPRKSSIN DIKQILREMS DDPDLLGLRR SGRAKKEPVR YNALGDSDTD DKPRRKGGRK
GSDDWNASDS GSGESSDDYK PSSRALSRPG GRRNLRAAPP RRGRQATSNL SDSDESNSEE
DTRSSSRIYS NKKIRRDYTT RRKGTKSKVS YKEDSDDQTD SDDIIEVTQD QMEAEEEDDN
KEIIEKVLDD RIGRVTATGS KTTIYNVQDN GDPNDGVDPA TEETEKQFLI KWKNWAHIHN
TWESYKTLKE QKVHGLKKLD NYIKKQDEIR EWKDQATPED IDYFDCQQEM VQELYQQHMH
VERIIAHSNQ KMANENNGYP DYLCKWEGLP YSECTWEEGE LVSRKFQVLV DEYNVRNKSQ
RTPTPAKYCK ALRYRPKFAP LKNQPSFLGG ENNQLVLRDY QLDGVNWLMH TWSKENSVIL
ADEMGLGKTI QTIGFLSILY NTFQVYGPNV LVVPLSTIAA WQREFKLWAP EMNVVIYLGD
ISSRNKIREH EWCHSGNKRL KFNVLVTTYE ILLKDKSFLG SVNWATLIVD EAHRLKNDDS
LLYKTLFEFN SNHRLLITGT PLQNSLKELW ALLHFIMPDK FYKWADFEEK HSSAQKTGFV
NLHKELESFL LRRVKKDVEK SLPAKTEQIL RVEMSSIQKQ YYRWILTKNY KALSKGLKGN
VSSFVNIIME LKKCCNHSQL IRPPEEEFSD RLASLVKGSG KLILLDKLLL RLKESGHRVL
IFSQMVRMLD ILAEYLQMRH FQYQRLDGSV RGDLRKQAMD HFNAEGSEDF CFLLSTRAGG
LGVNLATADT VIIFDSDWNP QNDLQAQARA HRIGQKNQVS VYRLVTKNSV EEDIVERAKR
KMVLDHLVIQ RMDTTGRTVL NRGIPSSNST PFNKDELTSI LKFGAEELFK ENDEDEDEPQ
VDIDEILKRA ETREVEENNT GVGDELLSQF KVVSFDNMED EEIEQTPGTR TEEEDKSWDS
IIPEADRRKI EEEEEQKRLL ELNLPPRSRK SLQQGQWMGV DYRLDAIACD AELQEKSESD
LQRLAEILIR NCEQAIEEAK NKTEQDNNEG GKKGNRGPSC KISSVSVNAQ AIVKAGQELE
PLAATIPADA DERKRYQLPF KAKAVHWDCI WDVEEDSNLL KGIYEYGLGS WEAIKMDPSL
QLHDKILPDG IDLKPQGKHL ATRADYLLKV LKKNSSQENG GDTVSTGLGK PRKKRKGKPK
TTAEIIEKDF SDSEEDSRAN FNNNSAREET SRDSFFDQHK KKKKTLKPDK IPEEEDTLTR
DSVDIKKKKK KAAKKSKQND AMHFTAGAVP VPVALESEFT GELPAEVFSK CKEMMRPVKR
ALKRLDNPDE GMSDKEQLVH TRQCLLKIGD RINECMGHYN DPEVIKQWRS FLWIFVSKFT
EFDAKKLHKL YKHAYRRREE EQEHEGGNNK PQSSEKHGNH VEKHGEGKKH KRPPESGDGG
EKAAKKAQLE HRPKDHKSSA SVSNGPRHSA STNSLTHKHS VLDSSHDSNS NDRWTHASMR
TVPVHMGVRS IIQRGITMAM TPGSTMIGES ILPVMHIIAI EVIIHHQVTI LITITTVTTD
QITVVTGVLT MDSTVTATMA ATVPIVVVTS LIQTGSVKGT QSRTGDLRKT LDSMRTPAGS
NSCWVPPPSS VTPQHYRAGS PVHLPGSVCR HPPHHSQSGL CEHPNLD
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