ID K1S1Q1_CRAGI Unreviewed; 716 AA.
AC K1S1Q1;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=MutS-like protein 5 {ECO:0000313|EMBL:EKC41211.1};
GN ORFNames=CGI_10006580 {ECO:0000313|EMBL:EKC41211.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC41211.1};
RN [1] {ECO:0000313|EMBL:EKC41211.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC41211.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
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DR EMBL; JH815931; EKC41211.1; -; Genomic_DNA.
DR AlphaFoldDB; K1S1Q1; -.
DR HOGENOM; CLU_002472_8_0_1; -.
DR InParanoid; K1S1Q1; -.
DR OMA; METHQDG; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0007127; P:meiosis I; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF20; MUTS PROTEIN HOMOLOG 5; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 2.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 550..566
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
SQ SEQUENCE 716 AA; 80955 MW; EB14A4BF2D5F9F9B CRC64;
MNSTSGYGNS TLSHSFTCNQ ETMETGDSDS GDMDSTSINE VHRVMPDTVE DDQIYMSVLW
HNGKLGMAYY DTELTQIFML LDIVESDDFL FLKRILRQLH PTCVLLSSKQ DDRLVQTLKS
LVSTNSDAGN ISLASDDISL STEDSNKLQF LPSIDFNPDI CKRRILNLDL PGIPDHYTDT
EKTLYFSSLI SFDNITTIRA TGGLLKYLEK MRVGVELEDA SVRVPVMDLK VVTLDDQVSL
DDTAFSALQI FQKEAHPSVY KIGQGGAKEG LSLFGVCCDE LWFLRPIRDI DVIKQRQDAI
AFFVNPRNIE VFSTLTDCMK NIKNIVPVLK RMYQAQATVI DWQALYKISE AFKDDLHRIA
NLINKIVDFE ESKVVGRFVV KPNVDAELDD KKRTYNGLPD FMTKLAAEEL ERLSDDIQEC
NVIYLPQLGY LLAIPRLDYM QTEEDFEMPG LEFVSFIHDI FVSGLMIDQE TAIMHKLQNA
ILESYRTLIE VQDLCAELDC FVPAESAVIG CVDRIFTRIR TMDSVSVGLS TFMIDVNQMS
EALRDATERS LVVVDEFGKG TELVDGMALL CSCLSFWIDK GKSCPHVLVS THFHSIIHQQ
LLPESPMVKF LTMDSLTEEG ELLFLYQLVE GHARSSYASH VALQAGLPQE IVKRGKEVSE
LIRQNKPVYA IDTADTETHF KRSELIVKKF LDLDLETDDL ESFLRDFVMP TSEGKL
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