ID   K1TKZ9_9ZZZZ            Unreviewed;       289 AA.
AC   K1TKZ9;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=3-dehydroquinate synthase {ECO:0000313|EMBL:EKC66995.1};
DE            EC=4.2.3.4 {ECO:0000313|EMBL:EKC66995.1};
DE   Flags: Fragment;
GN   ORFNames=OBE_05667 {ECO:0000313|EMBL:EKC66995.1};
OS   human gut metagenome.
OC   unclassified sequences; metagenomes; organismal metagenomes.
OX   NCBI_TaxID=408170 {ECO:0000313|EMBL:EKC66995.1};
RN   [1] {ECO:0000313|EMBL:EKC66995.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=22891823; DOI=10.1111/j.1462-2920.2012.02845.x;
RA   Ferrer M., Ruiz A., Lanza F., Haange S.B., Oberbach A., Till H.,
RA   Bargiela R., Campoy C., Segura M.T., Richter M., von Bergen M., Seifert J.,
RA   Suarez A.;
RT   "Microbiota from the distal guts of lean and obese adolescents exhibit
RT   partial functional redundancy besides clear differences in community
RT   structure.";
RL   Environ. Microbiol. 15:211-226(2013).
CC   -!- COFACTOR:
CC       Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC         Evidence={ECO:0000256|ARBA:ARBA00001911};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKC66995.1}.
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DR   EMBL; AJWZ01003885; EKC66995.1; -; Genomic_DNA.
DR   AlphaFoldDB; K1TKZ9; -.
DR   GO; GO:0003856; F:3-dehydroquinate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008652; P:amino acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd08195; DHQS; 1.
DR   Gene3D; 3.40.50.1970; -; 1.
DR   Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR   InterPro; IPR030960; DHQS/DOIS.
DR   PANTHER; PTHR43622; 3-DEHYDROQUINATE SYNTHASE; 1.
DR   PANTHER; PTHR43622:SF1; 3-DEHYDROQUINATE SYNTHASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01761; DHQ_synthase; 1.
DR   SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:EKC66995.1};
KW   NAD {ECO:0000256|ARBA:ARBA00023027}.
FT   DOMAIN          103..289
FT                   /note="3-dehydroquinate synthase"
FT                   /evidence="ECO:0000259|Pfam:PF01761"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EKC66995.1"
FT   NON_TER         289
FT                   /evidence="ECO:0000313|EMBL:EKC66995.1"
SQ   SEQUENCE   289 AA;  31120 MW;  E56DA3100A929517 CRC64;
     SQPGGELALG LLDEVGHEAV ERTEDRTVQD NGGLLVMKTV EVDAAVRYNI VIDKGILPKS
     GDMIKEVTSA ERVAVITDDT VDKLYSDVVM KSLSDAGFET FKFVFPHGEK SKNISTFSSI
     LEFLAESGLT RTDALVALGG GVVGDVAGFA SASYLRGIDF IQIPTTLLAC VDSSVGGKTA
     IDLKAGKNLA GAFYQPKLVI ADFETLSTLT DGIFADGMAE VIKYGVIFDK AFFEFLRDNE
     AKDNLEYVIT RCVELKRDIV NADEKEKGVR ALLNFGHTVG HAIEKCSGY
//