ID K1W8W7_MARBU Unreviewed; 617 AA.
AC K1W8W7;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Nucleolar GTP-binding protein 2 {ECO:0000256|ARBA:ARBA00022127, ECO:0000256|RuleBase:RU364023};
GN ORFNames=MBM_08348 {ECO:0000313|EMBL:EKD13630.1};
OS Marssonina brunnea f. sp. multigermtubi (strain MB_m1) (Marssonina leaf
OS spot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Drepanopezizaceae; Drepanopeziza.
OX NCBI_TaxID=1072389 {ECO:0000313|EMBL:EKD13630.1, ECO:0000313|Proteomes:UP000006753};
RN [1] {ECO:0000313|EMBL:EKD13630.1, ECO:0000313|Proteomes:UP000006753}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MB_m1 {ECO:0000313|EMBL:EKD13630.1,
RC ECO:0000313|Proteomes:UP000006753};
RX PubMed=22876864; DOI=10.1186/1471-2164-13-382;
RA Zhu S., Cao Y.-Z., Jiang C., Tan B.-Y., Wang Z., Feng S., Zhang L.,
RA Su X.-H., Brejova B., Vinar T., Xu M., Wang M.-X., Zhang S.-G.,
RA Huang M.-R., Wu R., Zhou Y.;
RT "Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-
RT evolution.";
RL BMC Genomics 13:382-382(2012).
CC -!- FUNCTION: GTPase that associates with pre-60S ribosomal subunits in the
CC nucleolus and is required for their nuclear export and maturation.
CC {ECO:0000256|ARBA:ARBA00003892, ECO:0000256|RuleBase:RU364023}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU364023}.
CC -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2
CC subfamily. {ECO:0000256|RuleBase:RU364023}.
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DR EMBL; JH921449; EKD13630.1; -; Genomic_DNA.
DR RefSeq; XP_007296237.1; XM_007296175.1.
DR AlphaFoldDB; K1W8W7; -.
DR STRING; 1072389.K1W8W7; -.
DR GeneID; 18764283; -.
DR KEGG; mbe:MBM_08348; -.
DR eggNOG; KOG2423; Eukaryota.
DR HOGENOM; CLU_011106_4_0_1; -.
DR InParanoid; K1W8W7; -.
DR OMA; RTQGFNH; -.
DR OrthoDB; 2879109at2759; -.
DR Proteomes; UP000006753; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd01858; NGP_1; 1.
DR Gene3D; 1.10.1580.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR030378; G_CP_dom.
DR InterPro; IPR024929; GNL2_CP_dom.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR023179; GTP-bd_ortho_bundle_sf.
DR InterPro; IPR012971; NOG2_N_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11089; GTP-BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR11089:SF9; NUCLEOLAR GTP-BINDING PROTEIN 2; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR Pfam; PF08153; NGP1NT; 1.
DR PRINTS; PR00326; GTP1OBG.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51721; G_CP; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU364023};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU364023};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364023};
KW Reference proteome {ECO:0000313|Proteomes:UP000006753}.
FT DOMAIN 225..386
FT /note="CP-type G"
FT /evidence="ECO:0000259|PROSITE:PS51721"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 483..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 489..516
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..548
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..584
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 617 AA; 67905 MW; 23CCD3BD4940ED16 CRC64;
MGQGKKEANR KAKAPGDGMA NVKVKGENFY RSAKKAKLLK TMNDTGTGKH NAAGELTQAA
KFQSKSVPVA RIEPNRKWFT NSRVIGQDAL NSFREAMAER ASDPYSVLLK SNKLPMSLIR
DGEGKNGIKQ HQAKMTVEAS PFSDVFGPHA QRKRVKIGVS SLEDLAEQSV ANHDIYLERL
EQAHLLSGNS MEDREAIGES AIPDHGYASS AKEAIFNKGQ SKRIWNELYK VIDSSDVVIH
VLDARDPIGT RCRSVEKYIK EEAPHKHLIF VLNKCDLVPT GVAAAWVRHL SKDYPTLAFH
ASITNSFGKG SLIQLLRQFS SLHSDRKQIS VGFIGYPNTG KSSIINTLRK KKVCTVAPIP
GETKVWQYIT LMKRIYLIDC PGVVPPSSTD TPQDILLRGV VRVENVEHPE QYIPAVLSKT
KPQHIERTYQ LKGYNGHIEF LELLARKGGR LLHGGEPDVD GVAKMVLNDF LRGKIPWFTP
PPLLEGTEAE KGIEGRAGRL GEMGKKRKRE DESVADALDP DTSVLDLDGE EEFKGFSDDD
DEGGAALDDV VGDVDQAFGL DSEDEDSEAG PDEKEDDAEE EDDAEAAKAQ LQGALHDVNA
VSNLGGRNPS KKKRQKT
//
