ID K1X6Z3_MARBU Unreviewed; 352 AA.
AC K1X6Z3;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Radical S-adenosyl methionine domain-containing protein 2 {ECO:0000313|EMBL:EKD20856.1};
GN ORFNames=MBM_01538 {ECO:0000313|EMBL:EKD20856.1};
OS Marssonina brunnea f. sp. multigermtubi (strain MB_m1) (Marssonina leaf
OS spot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Drepanopezizaceae; Drepanopeziza.
OX NCBI_TaxID=1072389 {ECO:0000313|EMBL:EKD20856.1, ECO:0000313|Proteomes:UP000006753};
RN [1] {ECO:0000313|EMBL:EKD20856.1, ECO:0000313|Proteomes:UP000006753}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MB_m1 {ECO:0000313|EMBL:EKD20856.1,
RC ECO:0000313|Proteomes:UP000006753};
RX PubMed=22876864; DOI=10.1186/1471-2164-13-382;
RA Zhu S., Cao Y.-Z., Jiang C., Tan B.-Y., Wang Z., Feng S., Zhang L.,
RA Su X.-H., Brejova B., Vinar T., Xu M., Wang M.-X., Zhang S.-G.,
RA Huang M.-R., Wu R., Zhou Y.;
RT "Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-
RT evolution.";
RL BMC Genomics 13:382-382(2012).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; JH921429; EKD20856.1; -; Genomic_DNA.
DR RefSeq; XP_007289427.1; XM_007289365.1.
DR AlphaFoldDB; K1X6Z3; -.
DR STRING; 1072389.K1X6Z3; -.
DR GeneID; 18757473; -.
DR KEGG; mbe:MBM_01538; -.
DR eggNOG; ENOG502QQMH; Eukaryota.
DR HOGENOM; CLU_049058_1_0_1; -.
DR InParanoid; K1X6Z3; -.
DR OMA; FRIRQWC; -.
DR OrthoDB; 3671494at2759; -.
DR Proteomes; UP000006753; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; NF038283; viperin_w_prok; 1.
DR PANTHER; PTHR21339; RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR21339:SF0; RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SFLD; SFLDF00318; Viperin; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006753};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 46..270
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 352 AA; 39756 MW; 5DCAF68AEE5812E8 CRC64;
MSNPLAVLVL LATLLLSIGI YLYTFRPSTR SSLNASAKPA AAAADDIIPV SVNYFFTRHC
NAECGFCFHT ETSSYKLPLD KACEGLRLLA KDGMEKVNFA GGEPFLYPKY LGELCRYCKE
DLKLPSVSIV SNGTKVTEKW LREFGPFVDI LAISCDSINP ETNAAIGRAD RGSGKPFDNV
GKLFEIRDWC MLYGVRFKLN TVVCSLNWNE DMSEMVEQLG PFRWKVFQVL VVKGQNDGDK
RKRDATKFIV TDEQYQEFCR KHEHLKCMIP EPNSSMKSSY LLIDEYMRFL DKGDGEEKVS
DSILEVGVQK AIKQVRWDQE EFRKRGGVYD WSKLTETTGG CSGAAAIKNL EW
//
