ID K1XB24_9BACT Unreviewed; 371 AA.
AC K1XB24;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Methionyl/Leucyl tRNA synthetase domain-containing protein {ECO:0000259|Pfam:PF09334};
DE Flags: Fragment;
GN ORFNames=ACD_87C00127G0001 {ECO:0000313|EMBL:EKD22171.1};
OS uncultured bacterium.
OC Bacteria; environmental samples.
OX NCBI_TaxID=77133 {ECO:0000313|EMBL:EKD22171.1};
RN [1] {ECO:0000313|EMBL:EKD22171.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23019650; DOI=10.1126/science.1224041;
RA Wrighton K.C., Thomas B.C., Sharon I., Miller C.S., Castelle C.J.,
RA VerBerkmoes N.C., Wilkins M.J., Hettich R.L., Lipton M.S., Williams K.H.,
RA Long P.E., Banfield J.F.;
RT "Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated
RT bacterial phyla.";
RL Science 337:1661-1665(2012).
CC -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC {ECO:0000256|RuleBase:RU363039}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKD22171.1}.
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DR EMBL; AMFJ01037181; EKD22171.1; -; Genomic_DNA.
DR AlphaFoldDB; K1XB24; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004825; F:methionine-tRNA ligase activity; IEA:InterPro.
DR GO; GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00814; MetRS_core; 1.
DR Gene3D; 2.170.220.10; -; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR023457; Met-tRNA_synth_2.
DR InterPro; IPR015413; Methionyl/Leucyl_tRNA_Synth.
DR InterPro; IPR033911; MetRS_core.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR43326:SF1; METHIONINE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43326; METHIONYL-TRNA SYNTHETASE; 1.
DR Pfam; PF09334; tRNA-synt_1g; 2.
DR PRINTS; PR01041; TRNASYNTHMET.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000256|RuleBase:RU363039};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363039};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363039};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU363039};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW ECO:0000256|RuleBase:RU363039}.
FT DOMAIN 5..147
FT /note="Methionyl/Leucyl tRNA synthetase"
FT /evidence="ECO:0000259|Pfam:PF09334"
FT DOMAIN 149..360
FT /note="Methionyl/Leucyl tRNA synthetase"
FT /evidence="ECO:0000259|Pfam:PF09334"
FT NON_TER 371
FT /evidence="ECO:0000313|EMBL:EKD22171.1"
SQ SEQUENCE 371 AA; 43163 MW; EF1BF043E5507CE2 CRC64;
MEHTFYITTP IYYVNASPHI GHAYTTIVAD VLARYHRLRG FRTFFSTGTD EHGDKIVEAA
QKAGVTPQAY ADQISAQFRA LWPELAVTND VFVRTTDPNH VETVRRILQK VHEGGDIYFG
QYEGFYCVGC ERFYMEKELV GGRCPQHETV PEHRKESNYF FRMSRYQEWL IRHISEHPDF
IRPERYRNEA LAFLRDPLED LCISRPKSRL TWGITLPFDE NYVTYVWFDA LINYVTAIGY
PEGENFRTFW PVAEHLIAKD ILKPHGIYWP TMLKAAGIEP YRNLNVHGYW NIDQSKMSKS
LGNVIRPLDL KDKYGLDPFR YFLLRDMVFG LDSSFSEEAF IQRINSDLAN DLGNLVSRTM
AMAVKYAGDC V
//
