ID K1YD56_9BACT Unreviewed; 416 AA.
AC K1YD56;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 28-JUN-2023, entry version 32.
DE RecName: Full=Ketosynthase family 3 (KS3) domain-containing protein {ECO:0000259|PROSITE:PS52004};
GN ORFNames=ACD_75C01964G0016 {ECO:0000313|EMBL:EKD35291.1};
OS uncultured bacterium.
OC Bacteria; environmental samples.
OX NCBI_TaxID=77133 {ECO:0000313|EMBL:EKD35291.1};
RN [1] {ECO:0000313|EMBL:EKD35291.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23019650; DOI=10.1126/science.1224041;
RA Wrighton K.C., Thomas B.C., Sharon I., Miller C.S., Castelle C.J.,
RA VerBerkmoes N.C., Wilkins M.J., Hettich R.L., Lipton M.S., Williams K.H.,
RA Long P.E., Banfield J.F.;
RT "Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated
RT bacterial phyla.";
RL Science 337:1661-1665(2012).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKD35291.1}.
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DR EMBL; AMFJ01032633; EKD35291.1; -; Genomic_DNA.
DR AlphaFoldDB; K1YD56; -.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 7..412
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 416 AA; 44869 MW; F4A77973BC284CFF CRC64;
MQKYMQSSRI VITGIGLAAP NASTLKEFRQ KLVNGTSEIK EIDLRYFGKA PAGICSFPET
LYRKKKENKK GTRAGCLGVY CANEALRDGK LDISTYSPAR IGVYIGLTEH GTVETENEVY
NISQYDYNVD YWTHHHNPRT VLNNPAGEIT MNLGITGPHY VIGAACAAGN ASLIQAVQML
KLGEIDMAIA GGISESVGSF GIFASFKAQG ALAEADDPRL ASRPFDLARN GIVISEGACL
YVVEHLDKAV ARGAHIYGEI VGYAMNSDAR DFVLPYGKRQ AECMRLALQR ANLQPEEIDL
INTHATGTKQ GDIEECKAIR EVFGNCSSTY INNTKSIIGH AMGAAGVLEL AGNLPSFDDG
IIHPTINIEN LDPECALANL VVNKAIQVDS VATLLNNSFG MVGINSTVIV KKYTGE
//
