ID K1ZV58_9BACT Unreviewed; 560 AA.
AC K1ZV58;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00012418};
DE EC=2.7.7.6 {ECO:0000256|ARBA:ARBA00012418};
GN ORFNames=ACD_61C00175G0003 {ECO:0000313|EMBL:EKD53036.1};
OS uncultured bacterium.
OC Bacteria; environmental samples.
OX NCBI_TaxID=77133 {ECO:0000313|EMBL:EKD53036.1};
RN [1] {ECO:0000313|EMBL:EKD53036.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23019650; DOI=10.1126/science.1224041;
RA Wrighton K.C., Thomas B.C., Sharon I., Miller C.S., Castelle C.J.,
RA VerBerkmoes N.C., Wilkins M.J., Hettich R.L., Lipton M.S., Williams K.H.,
RA Long P.E., Banfield J.F.;
RT "Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated
RT bacterial phyla.";
RL Science 337:1661-1665(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKD53036.1}.
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DR EMBL; AMFJ01025667; EKD53036.1; -; Genomic_DNA.
DR AlphaFoldDB; K1ZV58; -.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd02655; RNAP_beta'_C; 1.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 1.10.150.390; -; 1.
DR Gene3D; 1.10.1790.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF54; DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 4: Predicted;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 149..464
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04998"
SQ SEQUENCE 560 AA; 61052 MW; B303B847B6DCE235 CRC64;
MFHRAIKELD IKRVVRLIDG VKNIGFAYST ISGLSFAISD NEMYSEKAAV IEGGNQKAKE
IEENYNAGLI TNEERRKLTI QMWMDTAEDL AEKTWQEFSE ENPVRLIIDT GMGRITKNTI
KQLSAMRGIN VDPLGNMVEL PTKGNFREGL NIFEYVTSIR GSRKGLTDTA LRTADAGYLT
RRLVDVSHDA IIRAEDCGTD EFVTISTEDN RGKIFEKRIN SRFAAKKVVS PETHKVLVGA
GEMITEEIAA EIAKSGIKEV EVRSPLTCKM RFGLCVKCYG NSLASNSIAV IGDPVGVTAA
QSIGEPGTQL TMRTKHSGGV AGVDVTQGLP RVTELFEVRQ PKLVAPISEV SGKVKIVETD
NGNLVTVTPT GKKDDRKEYL IPLAMPLKVE DGELIAIGTQ LAVGGVDIKE LLKIKGLRSA
QNYLIGEIQS IYESQGIGIH DKHFEVIVRK MCDYVRIDSL GDTSLVAGDV ISRGSYEMAN
EAIIAQGGEP ATATNLILGT IRAALHTDSW LSAASFQDTT SVLTDAATQG KIDHLVGMKE
NVIIGRLVPT SKLRARIENI
//
