ID   K2AKF0_9BACT            Unreviewed;       209 AA.
AC   K2AKF0;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=S-adenosyl-L-homocysteine hydrolase {ECO:0000313|EMBL:EKD62106.1};
DE            EC=3.3.1.1 {ECO:0000313|EMBL:EKD62106.1};
DE   Flags: Fragment;
GN   Name=ahcY {ECO:0000313|EMBL:EKD62106.1};
GN   ORFNames=ACD_52C00301G0001 {ECO:0000313|EMBL:EKD62106.1};
OS   uncultured bacterium.
OC   Bacteria; environmental samples.
OX   NCBI_TaxID=77133 {ECO:0000313|EMBL:EKD62106.1};
RN   [1] {ECO:0000313|EMBL:EKD62106.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23019650; DOI=10.1126/science.1224041;
RA   Wrighton K.C., Thomas B.C., Sharon I., Miller C.S., Castelle C.J.,
RA   VerBerkmoes N.C., Wilkins M.J., Hettich R.L., Lipton M.S., Williams K.H.,
RA   Long P.E., Banfield J.F.;
RT   "Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated
RT   bacterial phyla.";
RL   Science 337:1661-1665(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKD62106.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AMFJ01022743; EKD62106.1; -; Genomic_DNA.
DR   AlphaFoldDB; K2AKF0; -.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1480; Adenosylhomocysteinase-like; 1.
DR   InterPro; IPR042172; Adenosylhomocyst_ase-like_sf.
DR   InterPro; IPR000043; Adenosylhomocysteinase-like.
DR   InterPro; IPR020082; S-Ado-L-homoCys_hydrolase_CS.
DR   PANTHER; PTHR23420; ADENOSYLHOMOCYSTEINASE; 1.
DR   PANTHER; PTHR23420:SF0; ADENOSYLHOMOCYSTEINASE; 1.
DR   Pfam; PF05221; AdoHcyase; 1.
DR   SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR   PROSITE; PS00738; ADOHCYASE_1; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:EKD62106.1};
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   One-carbon metabolism {ECO:0000256|ARBA:ARBA00022563}.
FT   NON_TER         209
FT                   /evidence="ECO:0000313|EMBL:EKD62106.1"
SQ   SEQUENCE   209 AA;  22649 MW;  648DD585D173E1D7 CRC64;
     MPSFVKHDVA DIKLAGEGKL KIEWAGQQMP VLQLIKERFS REKPLKGITL GACLHVTSET
     ANLMLALKAG GAKLALCASN PLSTQDSVAA SLVKDFGIPT FAIKGEDNQT YYRHLQAVLG
     FKPNVTMDDG ADLVTALQKL KIKYHLPAFA TLKALQAGKS KIQIKNQKGE SWEFLGSSEE
     TTTGVIRLKA MEKDKALKVP VVAVNDSDT
//