ID   K2BIE3_9BACT            Unreviewed;       420 AA.
AC   K2BIE3;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Phosphoribosylformylglycinamidine synthase II {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=ACD_45C00197G0003 {ECO:0000313|EMBL:EKD73752.1};
OS   uncultured bacterium.
OC   Bacteria; environmental samples.
OX   NCBI_TaxID=77133 {ECO:0000313|EMBL:EKD73752.1};
RN   [1] {ECO:0000313|EMBL:EKD73752.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23019650; DOI=10.1126/science.1224041;
RA   Wrighton K.C., Thomas B.C., Sharon I., Miller C.S., Castelle C.J.,
RA   VerBerkmoes N.C., Wilkins M.J., Hettich R.L., Lipton M.S., Williams K.H.,
RA   Long P.E., Banfield J.F.;
RT   "Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated
RT   bacterial phyla.";
RL   Science 337:1661-1665(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKD73752.1}.
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DR   EMBL; AMFJ01018865; EKD73752.1; -; Genomic_DNA.
DR   AlphaFoldDB; K2BIE3; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0004642; F:phosphoribosylformylglycinamidine synthase activity; IEA:InterPro.
DR   GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
DR   CDD; cd02204; PurL_repeat2; 1.
DR   Gene3D; 3.90.650.10; PurM-like C-terminal domain; 1.
DR   Gene3D; 3.30.1330.10; PurM-like, N-terminal domain; 1.
DR   InterPro; IPR010074; PRibForGlyAmidine_synth_PurL.
DR   InterPro; IPR010918; PurM-like_C_dom.
DR   InterPro; IPR036676; PurM-like_C_sf.
DR   InterPro; IPR016188; PurM-like_N.
DR   InterPro; IPR036921; PurM-like_N_sf.
DR   PANTHER; PTHR43555; PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE SUBUNIT PURL; 1.
DR   PANTHER; PTHR43555:SF1; PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE SUBUNIT PURL; 1.
DR   Pfam; PF00586; AIRS; 1.
DR   Pfam; PF02769; AIRS_C; 1.
DR   SUPFAM; SSF56042; PurM C-terminal domain-like; 1.
DR   SUPFAM; SSF55326; PurM N-terminal domain-like; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT   DOMAIN          121..241
FT                   /note="PurM-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00586"
FT   DOMAIN          258..395
FT                   /note="PurM-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02769"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EKD73752.1"
SQ   SEQUENCE   420 AA;  45644 MW;  FB3CBE5FF12DD14B CRC64;
     NDTFALPDIS SGAQATVIGK IRTDGIYSVK YQGDEIIHAR ACDITKGILY DRPYAARVKQ
     FSEPLLPAPS DFNAVLLELL SHENIASRAP LFEMYDKQVQ GRTVLEAGEA DAGVMQPFND
     DTYPIEIRHV GIALSLDQCP RYNKIDPYWG AVNAVVEAVR NVAAVGALPQ AITDCLCFGN
     PEKPEHMWEL TEAVRGIAEA CQAIGLKEYP GAALPVISGN VSLYNESKSG AIPASPMISC
     LGNLPDVKKV ITKNLQQTGS LLILIGERKD ECGGGVYYDL QGELGANVPK PDLRCIAAEI
     HALHDAIQQE LVLAAHDISE GGVAVAMAEM TFKHQIGVSI DIPGKLSNEK KLFGETGGFI
     LEVKQDQFTA LQKLFSHYQV PFFIIGKTLA QPTLKMQQCI DLSVLTAKQS WENGLREKLV
//