ID   K2BXQ4_9BACT            Unreviewed;      4109 AA.
AC   K2BXQ4;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   22-FEB-2023, entry version 24.
DE   SubName: Full=von Willebrand factor, type A {ECO:0000313|EMBL:EKD78381.1};
GN   ORFNames=ACD_41C00354G0003 {ECO:0000313|EMBL:EKD78381.1};
OS   uncultured bacterium.
OC   Bacteria; environmental samples.
OX   NCBI_TaxID=77133 {ECO:0000313|EMBL:EKD78381.1};
RN   [1] {ECO:0000313|EMBL:EKD78381.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23019650; DOI=10.1126/science.1224041;
RA   Wrighton K.C., Thomas B.C., Sharon I., Miller C.S., Castelle C.J.,
RA   VerBerkmoes N.C., Wilkins M.J., Hettich R.L., Lipton M.S., Williams K.H.,
RA   Long P.E., Banfield J.F.;
RT   "Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated
RT   bacterial phyla.";
RL   Science 337:1661-1665(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKD78381.1}.
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DR   EMBL; AMFJ01017236; EKD78381.1; -; Genomic_DNA.
DR   CDD; cd00198; vWFA; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF00092; VWA; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..4109
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017280527"
FT   DOMAIN          2701..2910
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          1356..1389
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          3614..3635
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   4109 AA;  442370 MW;  9E0CE149F38601EB CRC64;
     MSKLRYKLIA LLCLFTVVFG VVAAPRAVQA IPVETTVDLP GTIQIGVDKI LEVLKNAALI
     GVKNALSAFL GKISYDAAVY IASGGTGQDA LVYDKSFGDY MAEAGDAAAG GLIEGFATAA
     GMDAAGLCNP GEDFLINLTI GLETNIGQPT VYRPACTLTE LGENWQSAYS DPEFGDFVQL
     QFEPTANPLG ISLEAQDLTL AAKLQAEEDA EKQRQEDGGF KATTESVSKT ILTPASVIQE
     DLAGTKQNVA WYSLQSTDNP VVEALNIFTS TLISKLLERA QKGLANLSSG SELSGLLGGE
     FSGTISGRSA AEAVFSELRQ PIFGSSGSFD VLSELTACPG EEELRDTNNC AIGAALQTAI
     QDGWTVQEFI DYQTEIGQSF TVANSEINSV TTQQIQNSEG ISETGITILK KYRVVPVGWQ
     VASDYIQSTA DTPTLKDLVD CYNYCGTADT ERNCSFLLVD EDGNTTDYSP YCRLVDPYWV
     LKAPQNFCER EAPGGTIVEA ENFDTDANTN TQESVVLSRM NYCADARGCI EEEQEGVCTA
     YGYCTEEERI YRFDGEICEE EYSSCETFTD DNGDPVSLVK TTLNYNDCAT DPDCQWYCKS
     QNEAGQFDCA GPTETYVSCS EDVTDNESDY GLSYDVSLDT NEACACTSTQ TCQVPAGSTT
     GDGDGNGLID YRECAVSNTD GSQSVCSLDD NCGASNSTYS SATGTCTCTV TNSGDVDLGS
     SSVDITVEDD SGADATQTCT LDDEDGDSSA DSCTSDYSTY SSAPVCSVAS AGLMNCGDVC
     YTDETGGTCT NSLGNTCTDG DATDSDSDDR ECLLSDSCSV SSGLYSCTSS DGNVCILGTI
     TEEPATVSDT IYFDRNVETC DSNDAGCTQY IRIKPDTNLI PNALFDYYDA DSNTINDSDG
     DGVLDATIDG DDLAFCTHDG SGCATDTNCI EDLNSDGDGL DADETEGQCI GWIQNTVTAY
     VLDGDFDSLL TPDVGNNFIQ LEAGSSVGTL EMTVDTGHSL ANRTFTFAYR GMTTGTCSDV
     SFTIGNGDGT DVSSAVTADS AGTDYEYTSD WADYTTTYTF ADATTDEDIT VAISASTSCN
     INIGATSLVE DDEFTDNYTN YAINNLTYLN GDTVSCEPED VGCELYVEEG ASEEDGIPGL
     ITNPDSDDCV DASGNYNYDN PSCNQCNGDP EQDQDDDYYE GCDFYQEVPL DSTVPLTSDP
     LPGWLVSGTD AYEGTIKRLG GYCEGDSTTH CYEDTECSSG SCIAQLSIVP SSGGSCSVSA
     VGCEEYTNLA AVEEGGEGLQ YFTELKQCVR RDDQETAVFY TFEGSDTAGV QVQDHTLKVD
     TTTNAPCTHL DLQSEEFNAD CVDSTDYTAA EQLEWDCGPD GDIDGDGNLN GTTDDTTANT
     DTTTDDEEYG TDADCRQYVT ADGDIFYRYA SQVIEASDDC TPLRNSTDTR VYFALPEASN
     DCSAEEVSCR EYKGTDSGSE ETIIDEDFSN NSTEDWSGAT STSNESVLQS GYSLQLHDDD
     TANATDDEIS YELFTTEDTE TLGLLEDGDS YVLTFWAKAD DGGTLLASLD YETTAGSNYY
     FTTDGSSTTS STITLDPNNE DGWQFYAVGP VILPNGTNLD DGDEYFKLQY TGTAGTSEAY
     IDTVVLSQSN SQYIIQDSAR ACNNFEGCRL YEDRDNNDHY LKSFKRLCED SAVGCEAMLA
     TQQSANPFTE AYNLDNEYDQ DDVIVQYDQP VTLVYNEDNE CSSTVMGCTE FGLADVDDRT
     GEIIDYESEY LLDLPDSYSS TLCEQPQLSC REYTSEYDGT VYFKDPGEKL CELKEYTTSS
     NTFTGWFKLD TTASEPDCPL QYDFFGYGEN YASQPLGGVC NSNSVHHDTD GTALDEKVGT
     LCSQDADCYP EDWDESIDGR PRCISSIDDD VDLYDDGVHQ YVDYTDDGVS LSNVLTDFGW
     AGACPDDQSG CSEYMDPYSP NIVEENSNWS FEYDVLDDDN VQYASDGTPN GFPDNWMIPY
     NMTETNDDTN GDGIVDDEDD QSFTEIDLDA DGVVDISTSC TTADAVITSF TGETLVAHDG
     ASALKLAGDC VVEQTNALTI AVDKTYNVQA MVKMSKDYLD DGSNTPAEFS VGVHFYDIDN
     ELMAVDDVTL YLAADHATVD YEDGGDETDG LSYWYRFQGQ FGLGTAVPIP DQGICSNTTF
     ANRVPCETFG GTWTENLAAT AAVFIVNHSS NDIYFDAVSL KEVDKYYYLD YTVDGTVERE
     QQDGTNTCIN QDTEEGEITS DGGCVAFRDT TSDTQNYAQD GLDCTTCLLS PNSDSCRYVV
     DACDTNAVLK VKKDRVCSEW ISCVTSSLIE NADGTVSSEC SEINRCDELD EDGNCSSNLV
     DGLQKPGEYD EYSSSTDIHY STANGDNDEL SAIRNLTGYS KVGLTWDDVL YCDGGPSDGV
     RCSSDANCVN TAISCDAGVC SNDSSASCST VDDCYGEGDT GTCTIPFSTE GYYPYGWMPE
     VGLSGSSTGE DLIEINDFEQ LYCAGTNADT SLPCINNATD PSGAGDPGHC FSTSLKTKVE
     SDPDGELTYA DFVYVDESGS NVGTSFEASD PLHATLAFCP NSPNFGTYWP FEGGSAYSYT
     NAGWQPMGDD SSIFVTQFQD YQNCPAPCAD IDLNNVLQVG SDAADEAFAG GASYDLVDNV
     TADGTYALSF DARYVSDFTG VDEGGTPSTV SICLNHSGIG DAAGDELERK DCFVNGFGEA
     DIVFAIDTSG SMGSEITAVV TAVPDLAEQL SSAGIDTQFA LVDMDDNDRT DASATDDRGN
     HIDLDFTSDV SDFQAAVNAM SAESSTVDPT NAIYEVANNS LFDGESLTYR ANAQKFLVVV
     TDTGDEISND IGRGSAEDAA IAANLPVFVI TSGSYECADG DADDDDPCTN FYDGLTEATG
     GDTYSYDPTG STSLDWAADT NIIDDLFESI IDNIDIFQFS TDMETYTLGP IVAEQLAIDE
     DAGEQGLTTV TTALEFIGSD GNSFQIDNVS LLPVLEVNQD LNPIGRTCRA YPEEDSTQCS
     YVEQTGTQFQ GWKGYCLEVD PLNINRCITW WPMDVLEGET SLVQREASGY SGRSSVYHCL
     VSKGLEHPGF CDAGDYDSGD SANDYNGDGN AANDWGGAPI CTEGATCGSG TCFQGGIYKL
     DDTNSASRIE EHDDLTDDYE EDSTTSGGQC GVVEDSELDC ATWQGGGSCS DTTYTTQEDC
     EDPSVGGTWS DETDIMNNTA ILDTGDCIDI QTTASDGAGN DHYADYDDSE YSSLVADSYC
     FYDVDGATGA EVRSTRSCST DTQCQTPDTT NTYSCASLAC ESGNTSCGYH DSETSSECAS
     VASVTNDNPY EARLLTWDMP DPYETAYQNA LADYLDNGLI TAVAATCIVS GALSFTPPCL
     AILITVAIDA NNQARWGAAE RGVVVRLPAN ELMRNIHASE IESLEFFTGS AGDGAGGRSE
     YKAWGQDQDL GYGSGKIWLT DLAQGAIQYD ESGNVVTDKN GNETCYSARD GDDIVGFGCY
     TWGLYDNHDM ELDTYTEESF PKSSQHGLDL VYTFVWSNFD WGTQIDDGQC NISCDETGGR
     CFSDISDDDL EEWSDSGCVD HAVKYLAGAK GIENRNVWYD IESNHSSFWS EFYEDDITNQ
     TADIISFTEN DIEESGNNKI WPDPDDQDDD DTLNGRHDGG NILSLYVDFN DEGYIQAVYV
     LEYYAAIDTE DNPVDFHWAM VETTFEDRMY VDVQTRESCA LVAESVSATG DERAWAARTN
     SVGYEINYGE DVSIPQDEPN EPYGSVSTQD GDPTEWDYIG ASAADWTSPD FSWNTLGQQP
     SVAMTGDTLQ IRGGHPMSCI GECESTACVG SPGNAGDSCS SDDDCGDGIC MGIGDTVISA
     DGQFSQQATT FSNFDDQVAA VAGEGRDRLK HVFANIDSFY LLNYVSTPYN TVDENGDTIS
     DYWDDGSGNV FDNMEQCTNN ERTGDLGSEE EYCGVLPSVT SSTIDDNSAL DVGNYEIGNG
     QSVTFQFTAN VDEQQKPLSK IYIDWGDGSE PTTENWEAEP TIHTYAHAYS CSPADGARYC
     YTSDDCSDVG QFCEFKPKIV LVDNWNWCSG AYDGDCSTGS YATEEECTDN DATWTDVGDH
     RYTVGATDIM ASCQSYDETS LTIRVDASN
//