ID K2C3Q3_9BACT Unreviewed; 39 AA.
AC K2C3Q3;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Heme exporter protein D {ECO:0000256|ARBA:ARBA00016461};
GN ORFNames=ACD_44C00049G0021 {ECO:0000313|EMBL:EKD75698.1};
OS uncultured bacterium.
OC Bacteria; environmental samples.
OX NCBI_TaxID=77133 {ECO:0000313|EMBL:EKD75698.1};
RN [1] {ECO:0000313|EMBL:EKD75698.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23019650; DOI=10.1126/science.1224041;
RA Wrighton K.C., Thomas B.C., Sharon I., Miller C.S., Castelle C.J.,
RA VerBerkmoes N.C., Wilkins M.J., Hettich R.L., Lipton M.S., Williams K.H.,
RA Long P.E., Banfield J.F.;
RT "Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated
RT bacterial phyla.";
RL Science 337:1661-1665(2012).
CC -!- FUNCTION: Required for the export of heme to the periplasm for the
CC biogenesis of c-type cytochromes. {ECO:0000256|ARBA:ARBA00002442}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004377}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004377}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the CcmD/CycX/HelD family.
CC {ECO:0000256|ARBA:ARBA00008741}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKD75698.1}.
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DR EMBL; AMFJ01018232; EKD75698.1; -; Genomic_DNA.
DR AlphaFoldDB; K2C3Q3; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:InterPro.
DR GO; GO:0015886; P:heme transport; IEA:InterPro.
DR InterPro; IPR007078; Haem_export_protD_CcmD.
DR NCBIfam; TIGR03141; cytochro_ccmD; 1.
DR Pfam; PF04995; CcmD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 39 AA; 4750 MW; 88E794283FA2AF01 CRC64;
MNVLIDFFHM GGYAFYVWWA YGISFFVLML NFIFVMCVR
//
