ID   K2CU10_9BACT            Unreviewed;       432 AA.
AC   K2CU10;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Methyltransferase {ECO:0000256|RuleBase:RU362026};
DE            EC=2.1.1.- {ECO:0000256|RuleBase:RU362026};
GN   ORFNames=ACD_23C01398G0004 {ECO:0000313|EMBL:EKD96570.1};
OS   uncultured bacterium.
OC   Bacteria; environmental samples.
OX   NCBI_TaxID=77133 {ECO:0000313|EMBL:EKD96570.1};
RN   [1] {ECO:0000313|EMBL:EKD96570.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23019650; DOI=10.1126/science.1224041;
RA   Wrighton K.C., Thomas B.C., Sharon I., Miller C.S., Castelle C.J.,
RA   VerBerkmoes N.C., Wilkins M.J., Hettich R.L., Lipton M.S., Williams K.H.,
RA   Long P.E., Banfield J.F.;
RT   "Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated
RT   bacterial phyla.";
RL   Science 337:1661-1665(2012).
CC   -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC       {ECO:0000256|RuleBase:RU362026}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKD96570.1}.
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DR   EMBL; AMFJ01009936; EKD96570.1; -; Genomic_DNA.
DR   AlphaFoldDB; K2CU10; -.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR002941; DNA_methylase_N4/N6.
DR   InterPro; IPR001091; RM_Methyltransferase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR13370:SF32; DNA ADENINE METHYLTRANSFERASE YHDJ; 1.
DR   PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR   Pfam; PF01555; N6_N4_Mtase; 1.
DR   PRINTS; PR00508; S21N4MTFRASE.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          80..368
FT                   /note="DNA methylase N-4/N-6"
FT                   /evidence="ECO:0000259|Pfam:PF01555"
SQ   SEQUENCE   432 AA;  49163 MW;  31778BA197385BBE CRC64;
     MAIGIPGRGK KSGMEQMRAK LPELRLEYPG KKPIEAILAT PPGRYYPNAI HCGGENRLYH
     ADNLGVLAAL VKDESIAGQV RLVYIDPPFA TSSAFHSRKQ NHAYDDHLVG AEFIEFLRER
     LVLIHQLLAD DGSLYMHLDE RMAFHFRVIL DEIFGERCYR NFIIRKKCNP KNYTRKTFGN
     VADYILFYTK SDSYVWNRPI EQWDQVKADK EYQYTDEKTG RRYKKVPIHA PGSRNGATGG
     EWRGMMPPPG KHWQYLPSTL DEMDARGDIY WSATGNPRRK IYLEDSNGIP VQDIWMDMRD
     AHNQNIHVTG YPTEKNPDLL ARIIEASSNP GDIVLDCFAG SGTTLSVAAL NGRRWIGVDK
     SDEAIKTILK RLECGTERMG DFVNDRKPKN LTLLLHNPVA DFTLYLEEDT QIKQRRSKAA
     KASEAPAATF VE
//