ID K2E1S1_9BACT Unreviewed; 381 AA.
AC K2E1S1;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:EKE12251.1};
GN ORFNames=ACD_13C00249G0015 {ECO:0000313|EMBL:EKE12251.1};
OS uncultured bacterium.
OC Bacteria; environmental samples.
OX NCBI_TaxID=77133 {ECO:0000313|EMBL:EKE12251.1};
RN [1] {ECO:0000313|EMBL:EKE12251.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23019650; DOI=10.1126/science.1224041;
RA Wrighton K.C., Thomas B.C., Sharon I., Miller C.S., Castelle C.J.,
RA VerBerkmoes N.C., Wilkins M.J., Hettich R.L., Lipton M.S., Williams K.H.,
RA Long P.E., Banfield J.F.;
RT "Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated
RT bacterial phyla.";
RL Science 337:1661-1665(2012).
CC -!- SIMILARITY: Belongs to the iron-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00007358}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKE12251.1}.
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DR EMBL; AMFJ01005536; EKE12251.1; -; Genomic_DNA.
DR AlphaFoldDB; K2E1S1; -.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd08551; Fe-ADH; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR InterPro; IPR001670; ADH_Fe/GldA.
DR InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR11496:SF102; ALCOHOL DEHYDROGENASE 4; 1.
DR Pfam; PF00465; Fe-ADH; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 14..366
FT /note="Alcohol dehydrogenase iron-type/glycerol
FT dehydrogenase GldA"
FT /evidence="ECO:0000259|Pfam:PF00465"
SQ SEQUENCE 381 AA; 42101 MW; 60BFE6339AE4ABEA CRC64;
MKDCWKFATP QYLKSGAGIS MTIFEYIKEL DAKKVYVVID PNLVKTNVLA KQILLRFEKI
DSCIFSDFGT NPTTNQVNNS VELFKKYNPD VIIAIGGGSA IDLTKATILT ALNGGIIEDY
LSGKKGDKPF IPFIAIPTTC GTGSEASPYA VIADPKQKKK RGIEDYNFLP KLVLLDSELV
ESLDKTILAG TAIDALAHVC ESFVSKKASE ITKSSARGIL LGLINNIEKA TFEKDSEHLF
AMLNTAFSSR LLYPRTGLTI AHALSHPLGA YTNIHHGCAV TFFLPESFKA NYIYNKNAFD
EAFNLLGFNN TDDFYAWFNG FINKSGMSEY IQTYLEHKEI LVGKIAHDAM ESSNIPSNPK
PVTEGDLVEV VNKSISYWNL K
//
