ID   K2EK73_9BACT            Unreviewed;       352 AA.
AC   K2EK73;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   22-FEB-2023, entry version 26.
DE   RecName: Full=IMP dehydrogenase/GMP reductase domain-containing protein {ECO:0000259|Pfam:PF00478};
GN   ORFNames=ACD_19C00079G0034 {ECO:0000313|EMBL:EKE06129.1};
OS   uncultured bacterium.
OC   Bacteria; environmental samples.
OX   NCBI_TaxID=77133 {ECO:0000313|EMBL:EKE06129.1};
RN   [1] {ECO:0000313|EMBL:EKE06129.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23019650; DOI=10.1126/science.1224041;
RA   Wrighton K.C., Thomas B.C., Sharon I., Miller C.S., Castelle C.J.,
RA   VerBerkmoes N.C., Wilkins M.J., Hettich R.L., Lipton M.S., Williams K.H.,
RA   Long P.E., Banfield J.F.;
RT   "Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated
RT   bacterial phyla.";
RL   Science 337:1661-1665(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKE06129.1}.
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DR   EMBL; AMFJ01007126; EKE06129.1; -; Genomic_DNA.
DR   AlphaFoldDB; K2EK73; -.
DR   GO; GO:0003938; F:IMP dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR   CDD; cd00381; IMPDH; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 2.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR005990; IMP_DH.
DR   InterPro; IPR001093; IMP_DH_GMPRt.
DR   PANTHER; PTHR11911:SF122; GMP REDUCTASE; 1.
DR   PANTHER; PTHR11911; INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; 1.
DR   Pfam; PF00478; IMPDH; 1.
DR   SMART; SM01240; IMPDH; 1.
DR   SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE   4: Predicted;
FT   DOMAIN          10..348
FT                   /note="IMP dehydrogenase/GMP reductase"
FT                   /evidence="ECO:0000259|Pfam:PF00478"
SQ   SEQUENCE   352 AA;  37514 MW;  6B6842FBCA1FCCF5 CRC64;
     MINLNDIPLA LSYDDVLLVP QYSNIKSRSD VDLSTQITPR VKLNIPLISI NMSDVTGVEM
     AVALGKLGGI GFLPRFDTPE NQAAMVGQVK KSKVLVGAAV GCKDDFLKRA EFLVKAGIDI
     ITLDVAHGGM QQAIDTTTEL KRRFGKTCDI ISGVVGTYDS AQALFKAGAD SVRVGVGPGT
     ICTTRIQTGF GVPQITAVIE ASRAARKFKK TILCDGGTKN SGDIVKGLAA GASAVIMGSQ
     FAGHDEAPGE IIIKNGIKYK AYNASTSLTE KIKHTKALKC LPASYTKHIE GVESLVLYKG
     PLKNTIEKWL ANIRSGYSYS GASNINELWQ NSKFIRVSPL GARESGAHDV IL
//