ID K2H8X0_9RHOB Unreviewed; 303 AA.
AC K2H8X0;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=HTH-type transcriptional regulator MetR {ECO:0000256|ARBA:ARBA00019365};
GN ORFNames=OCGS_2004 {ECO:0000313|EMBL:EKE44023.1};
OS Oceaniovalibus guishaninsula JLT2003.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Oceaniovalibus.
OX NCBI_TaxID=1231392 {ECO:0000313|EMBL:EKE44023.1, ECO:0000313|Proteomes:UP000006765};
RN [1] {ECO:0000313|EMBL:EKE44023.1, ECO:0000313|Proteomes:UP000006765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JLT2003 {ECO:0000313|EMBL:EKE44023.1,
RC ECO:0000313|Proteomes:UP000006765};
RX PubMed=23144420; DOI=10.1128/JB.01874-12;
RA Tang K., Liu K., Jiao N.;
RT "Draft Genome Sequence of Oceaniovalibus guishaninsula JLT2003T.";
RL J. Bacteriol. 194:6683-6683(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKE44023.1}.
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DR EMBL; AMGO01000046; EKE44023.1; -; Genomic_DNA.
DR RefSeq; WP_007427156.1; NZ_AMGO01000046.1.
DR AlphaFoldDB; K2H8X0; -.
DR STRING; 1231392.OCGS_2004; -.
DR PATRIC; fig|1231392.3.peg.2014; -.
DR eggNOG; COG0583; Bacteria.
DR OrthoDB; 155872at2; -.
DR Proteomes; UP000006765; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd08441; PBP2_MetR; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR037406; MetR_PBP2.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR30126:SF25; HTH-TYPE TRANSCRIPTIONAL REGULATOR METR; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methionine biosynthesis {ECO:0000256|ARBA:ARBA00023167};
KW Reference proteome {ECO:0000313|Proteomes:UP000006765};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..60
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 303 AA; 33386 MW; 205EEBDF253471BB CRC64;
MNIEFRHLRT VKAIHEAGGL GRAAARLNIT QSALSHQIKG LEDQAGVALF VRRSKPMTLS
AAGLKLLRAA ERILPEVAAL EAEFAGLVSG RAGRLHIAIE CHACFEWLFP VLEAFRRDWP
DVDVDIRPGL AFGALPALQR QEVDLVVSSD PETLPGVDFT PLFDYEPVFV ASSRHPLAAK
PFVVAEDFRD QTLITYPVER ARLDVFSQLL MPAGVEPAEV RQVELTAVIL LLVASQRGVA
VLPDWVVRDV RLQSDYVTRP LTKGGLTRRL YAATRSDETE APFMADLLRL TQTVPVKLQR
GAA
//
