ID K2KF61_9PROT Unreviewed; 587 AA.
AC K2KF61;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Peptidoglycan synthetase FtsI {ECO:0000313|EMBL:EKE76010.1};
GN ORFNames=P24_08856 {ECO:0000313|EMBL:EKE76010.1};
OS Oceanibaculum indicum P24.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Oceanibaculaceae; Oceanibaculum.
OX NCBI_TaxID=1207063 {ECO:0000313|EMBL:EKE76010.1, ECO:0000313|Proteomes:UP000006746};
RN [1] {ECO:0000313|EMBL:EKE76010.1, ECO:0000313|Proteomes:UP000006746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P24 {ECO:0000313|EMBL:EKE76010.1,
RC ECO:0000313|Proteomes:UP000006746};
RX PubMed=23209207; DOI=10.1128/JB.01859-12;
RA Lai Q., Shao Z.;
RT "Genome Sequence of Oceanibaculum indicum Type Strain P24.";
RL J. Bacteriol. 194:6942-6942(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKE76010.1}.
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DR EMBL; AMRL01000009; EKE76010.1; -; Genomic_DNA.
DR RefSeq; WP_008944378.1; NZ_AMRL01000009.1.
DR AlphaFoldDB; K2KF61; -.
DR STRING; 1207063.P24_08856; -.
DR PATRIC; fig|1207063.3.peg.1790; -.
DR eggNOG; COG0768; Bacteria.
DR Proteomes; UP000006746; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 1.10.150.770; -; 1.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006746};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 41..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 83..210
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 247..544
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 587 AA; 63508 MW; 02C58057FB7F93E5 CRC64;
MTRLFRNGFA RPATPEAPPP AHHVALEGVA KQALETGRTR LVIATALFAA VFAAVGLRLV
DVSVLSGASE PRLAETPRAN ASPSGRAEII DRNGLLLATS LATPSLYADP QAVLDPAEAA
RKLATVLPDL SEPELIAKLA TDRRFVWVKR NLTPRQKYEV NRLGIPGFYF QREERRFYPQ
GSAAAHVLGY TDVDGRGIAG IEKSFDEVLR SGGQPVQLSL DVRLQQIVRD SLLESIEEFK
AIGAAGLVMD VRSGEVLAMV SLPDYDPNQP GSITEEQQFN RATLGVYEMG STFKLFNHAM
ALDSGKVRMG GGYDASQPIR IARFTINDYH GKNRWLSVPE ILIHSSNIGS AKMALEVGAA
GQRAFMEKIG MLARQPIEIP EAGLPLAPSP WRDINVMTIS FGHGLSVSPL HLVSGVSALV
NGGMLHPATL LRREPGAAVQ GSRVIAERTS LQMRKLMRLV VEEGSGRNAD AKGYLVGGKT
GTAEKLNGRG YNRKARISSF VGAYPINDPR YVVLAMIDEP VGNKRTFGYA TGGWVAAPVV
NRIVARMAPM YGIPPIDENA PEIRRDLVVD IAPRDPSQNG SKRLASY
//
