ID K2KNH5_9PROT Unreviewed; 1031 AA.
AC K2KNH5;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=FAD-binding PCMH-type domain-containing protein {ECO:0000259|PROSITE:PS51387};
GN ORFNames=TH2_15627 {ECO:0000313|EMBL:EKF07334.1};
OS Thalassospira profundimaris WP0211.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Thalassospiraceae; Thalassospira.
OX NCBI_TaxID=1177928 {ECO:0000313|EMBL:EKF07334.1, ECO:0000313|Proteomes:UP000007365};
RN [1] {ECO:0000313|EMBL:EKF07334.1, ECO:0000313|Proteomes:UP000007365}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WP0211 {ECO:0000313|EMBL:EKF07334.1,
RC ECO:0000313|Proteomes:UP000007365};
RX PubMed=23209215; DOI=10.1128/JB.01903-12;
RA Lai Q., Shao Z.;
RT "Genome Sequence of Thalassospira profundimaris Type Strain WP0211.";
RL J. Bacteriol. 194:6956-6956(2012).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKF07334.1}.
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DR EMBL; AMRN01000008; EKF07334.1; -; Genomic_DNA.
DR RefSeq; WP_008891425.1; NZ_AMRN01000008.1.
DR AlphaFoldDB; K2KNH5; -.
DR PATRIC; fig|1177928.3.peg.3208; -.
DR eggNOG; COG0247; Bacteria.
DR eggNOG; COG0277; Bacteria.
DR Proteomes; UP000007365; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.30.70.2740; -; 1.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR InterPro; IPR009051; Helical_ferredxn.
DR InterPro; IPR006094; Oxid_FAD_bind_N.
DR InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR PANTHER; PTHR11748:SF119; D-2-HYDROXYGLUTARATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11748; D-LACTATE DEHYDROGENASE; 1.
DR Pfam; PF02913; FAD-oxidase_C; 1.
DR Pfam; PF01565; FAD_binding_4; 1.
DR Pfam; PF13183; Fer4_8; 1.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 74..306
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
SQ SEQUENCE 1031 AA; 114292 MW; 3D75D3DE1FA62D2A CRC64;
MSVPAPAATP VTNPVTNASN KSVIKKLPAL TPDRSLDSLT LGFLKTLEAE GKFAGEIHAD
FPTRLINATD NSVYQVMPTA VLQPKTRGDI NVVMELAGRE KFSEVKITPR GGGTGTNGQS
LNNTIILDTS KHLNNILGFD AERGLVHVEP GVVLDQLNAW LKPHGYFFPP AVSTASRATV
GGMIGSDSSG KGSRIYGKTS HYIHDMTTVL IDGTDFNTRA MNATEAKDTM DRADRVGQLY
KKVHDEIAPR RDQIKSTFPE MNRGLTGYNL KEAVSDTGDM NLSFLIAGAE GSLGMVKEIT
FRVIPMPKFK AVTVVRYDSF DSALRHVKTL VQFDPVAIES IDDKVMKLAE QDESWHMLGK
LLGTENSTTP TRGFNVVEFV GETEAEVAAK QTELKSYLEA NPTEDFSPIG FVQATDPAQI
AAIWSIRAKS VGLLGNLEGK RRATPFVEDT AVPPENLADF IAEFRALLDA EGLDYGMFGH
VDVGCLHVRP LLDMMDEEDE ARIRRVSDAV AALTKRYNGL IWGEHGKGFR GEYSPVYFGP
ELYDVLRRIK EAFDPEGQLN PGKIASPYSK NTPITAIDEA PMRGQFDRQI EDALRDEYLN
ATRCNGNGAC FNWDLMDAMC PSYKVTRSRV HSPKGRAGMI REWIRQLSVG TDPMNKDLAV
INGRDFSHDV YEAMAGCLSC KACAGQCPVK VDIPEMKSRF LETYHTRYKR PIKDHVIASL
ESMAPLLAKA PGLFNALQSI PPTPWIFKRF IGLTDLPKLH GQSLKSGLRA RGIGKFRQAE
LDSLSGDEKA KSVILVQDCF TTHYDTHVVL AHVDLLQRLG YRVFVPPYRP NGKAMHVKGF
LKRFDYQAKQ NDIVLGKIAK SGVPMIGIEA SVTLTYRQEY EQRLSNRPDY RVHLFHEWLA
GEIEHGRLTP PKIDNGVNMS APDAPARLFP HCTEKTSIPD VGVKWQKIFD AFGLKLTTEK
TGCCGMAGVY GHETRHQETS RELYELSWKK KVDATGPQNM LVTGYSCRCQ VDRYEGVKPQ
HPVEYLAKLI A
//
