ID K2L490_HELPX Unreviewed; 82 AA.
AC K2L490;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Cell division topological specificity factor {ECO:0000256|HAMAP-Rule:MF_00262};
GN Name=minE {ECO:0000256|HAMAP-Rule:MF_00262,
GN ECO:0000313|EMBL:EKE95128.1};
GN ORFNames=OUS_0611 {ECO:0000313|EMBL:EKE95128.1};
OS Helicobacter pylori R056a.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1145118 {ECO:0000313|EMBL:EKE95128.1, ECO:0000313|Proteomes:UP000006748};
RN [1] {ECO:0000313|EMBL:EKE95128.1, ECO:0000313|Proteomes:UP000006748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R056a {ECO:0000313|EMBL:EKE95128.1,
RC ECO:0000313|Proteomes:UP000006748};
RX PubMed=23661595; DOI=10.1111/2049-632X.12045;
RA Blanchard T.G., Czinn S.J., Correa P., Nakazawa T., Keelan M.,
RA Morningstar L., Santana-Cruz I., Maroo A., McCracken C., Shefchek K.,
RA Daugherty S., Song Y., Fraser C.M., Fricke W.F.;
RT "Genome sequences of 65 Helicobacter pylori strains isolated from
RT asymptomatic individuals and patients with gastric cancer, peptic ulcer
RT disease, or gastritis.";
RL Pathog. Dis. 68:39-43(2013).
CC -!- FUNCTION: Prevents the cell division inhibition by proteins MinC and
CC MinD at internal division sites while permitting inhibition at polar
CC sites. This ensures cell division at the proper site by restricting the
CC formation of a division septum at the midpoint of the long axis of the
CC cell. {ECO:0000256|ARBA:ARBA00025265, ECO:0000256|HAMAP-Rule:MF_00262}.
CC -!- SIMILARITY: Belongs to the MinE family. {ECO:0000256|ARBA:ARBA00008168,
CC ECO:0000256|HAMAP-Rule:MF_00262}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKE95128.1}.
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DR EMBL; AMOY01000005; EKE95128.1; -; Genomic_DNA.
DR RefSeq; WP_000051426.1; NZ_AMOY01000005.1.
DR AlphaFoldDB; K2L490; -.
DR PATRIC; fig|1145118.3.peg.604; -.
DR Proteomes; UP000006748; Unassembled WGS sequence.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0032955; P:regulation of division septum assembly; IEA:InterPro.
DR Gene3D; 3.30.1070.10; Cell division topological specificity factor MinE; 1.
DR HAMAP; MF_00262; MinE; 1.
DR InterPro; IPR005527; MinE.
DR InterPro; IPR036707; MinE_sf.
DR NCBIfam; TIGR01215; minE; 1.
DR Pfam; PF03776; MinE; 1.
DR SUPFAM; SSF55229; Cell division protein MinE topological specificity domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|HAMAP-Rule:MF_00262};
KW Cell division {ECO:0000256|HAMAP-Rule:MF_00262,
KW ECO:0000313|EMBL:EKE95128.1}.
SQ SEQUENCE 82 AA; 9584 MW; 542DA27170FF0A1A CRC64;
MSLFDFFKNK GSATTATDRL KLILAKERTL NLPYMEEMRK EIIAVIQKYT KYSDIHFKTL
DSNQSVETIE VEIILPKQLT NE
//