ID K2L4Y5_HELPX Unreviewed; 378 AA.
AC K2L4Y5;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Cation transport family protein {ECO:0000313|EMBL:EKE89624.1};
GN ORFNames=OUK_0770 {ECO:0000313|EMBL:EKE89624.1};
OS Helicobacter pylori R037c.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1145114 {ECO:0000313|EMBL:EKE89624.1, ECO:0000313|Proteomes:UP000006760};
RN [1] {ECO:0000313|EMBL:EKE89624.1, ECO:0000313|Proteomes:UP000006760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R037c {ECO:0000313|EMBL:EKE89624.1,
RC ECO:0000313|Proteomes:UP000006760};
RX PubMed=23661595; DOI=10.1111/2049-632X.12045;
RA Blanchard T.G., Czinn S.J., Correa P., Nakazawa T., Keelan M.,
RA Morningstar L., Santana-Cruz I., Maroo A., McCracken C., Shefchek K.,
RA Daugherty S., Song Y., Fraser C.M., Fricke W.F.;
RT "Genome sequences of 65 Helicobacter pylori strains isolated from
RT asymptomatic individuals and patients with gastric cancer, peptic ulcer
RT disease, or gastritis.";
RL Pathog. Dis. 68:39-43(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKE89624.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMOU01000004; EKE89624.1; -; Genomic_DNA.
DR RefSeq; WP_000461980.1; NZ_AMOU01000004.1.
DR AlphaFoldDB; K2L4Y5; -.
DR PATRIC; fig|1145114.3.peg.754; -.
DR Proteomes; UP000006760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833:SF9; POTASSIUM CHANNEL PROTEIN 2-RELATED; 1.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR Pfam; PF02080; TrkA_C; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS51202; RCK_C; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 32..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 137..265
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 281..366
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 378 AA; 42889 MW; 073E6192EA97B658 CRC64;
MFEKLKFFKI KKDDEIQPEV NLNSEIYEQF KVFRLPLILI QLLVLLGTLG YFALENYSLM
QAFFQTTYTM TATGFGALNE SQFGPISIFL TSILMFFGAG IIAFSVAILV SVVNKGTLTR
LIKEKGMIYK IARLKDHYVI CYHNEYTIEL SKQFRSAQIP FVVVDNDPSF EEEAIKHKYP
YYIIGDPHTN LAMLKTHLSS ARGVVALSKI LPVNVALMVS VRLFEKELKR KPYYIIASAH
SDEGLEKLKK LGADMVVSPT KLMAQRVSAM AVRPDMENIL ERFINKKDTL LDLEEVIVPK
TSWLVLRKLK EAHFREIAKA FVIGITQKDG KYIPMPDGET IIASESKLLM VGTSEGVATC
KQLIANHQRP KEVDYISL
//
