ID K2LRW3_HELPX Unreviewed; 284 AA.
AC K2LRW3;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Methyltransferase {ECO:0000256|RuleBase:RU362026};
DE EC=2.1.1.- {ECO:0000256|RuleBase:RU362026};
GN Name=dpnA {ECO:0000313|EMBL:EKE92655.1};
GN ORFNames=OUO_0018 {ECO:0000313|EMBL:EKE92655.1};
OS Helicobacter pylori R046Wa.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1145116 {ECO:0000313|EMBL:EKE92655.1, ECO:0000313|Proteomes:UP000006763};
RN [1] {ECO:0000313|EMBL:EKE92655.1, ECO:0000313|Proteomes:UP000006763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R046Wa {ECO:0000313|EMBL:EKE92655.1,
RC ECO:0000313|Proteomes:UP000006763};
RX PubMed=23661595; DOI=10.1111/2049-632X.12045;
RA Blanchard T.G., Czinn S.J., Correa P., Nakazawa T., Keelan M.,
RA Morningstar L., Santana-Cruz I., Maroo A., McCracken C., Shefchek K.,
RA Daugherty S., Song Y., Fraser C.M., Fricke W.F.;
RT "Genome sequences of 65 Helicobacter pylori strains isolated from
RT asymptomatic individuals and patients with gastric cancer, peptic ulcer
RT disease, or gastritis.";
RL Pathog. Dis. 68:39-43(2013).
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594, ECO:0000256|RuleBase:RU362026}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKE92655.1}.
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DR EMBL; AMOW01000001; EKE92655.1; -; Genomic_DNA.
DR RefSeq; WP_000582300.1; NZ_AMOW01000001.1.
DR AlphaFoldDB; K2LRW3; -.
DR PATRIC; fig|1145116.3.peg.17; -.
DR Proteomes; UP000006763; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR001091; RM_Methyltransferase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR13370:SF32; DNA ADENINE METHYLTRANSFERASE YHDJ; 1.
DR PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR PRINTS; PR00508; S21N4MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EKE92655.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EKE92655.1}.
FT DOMAIN 40..253
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
SQ SEQUENCE 284 AA; 32533 MW; 6A6FBA08B3389F2C CRC64;
MIIAHSNEIA HPIFKSQDQL FTLYQGDCNE VLPQFENAFD LIFADPPYFL SNDGLSIQSG
KIVSVNKGDW DKEDGINDID EFNYQWINNA KKALKNTGSL LISGTYHNIF SLGRILQKLD
FKILNLITWQ KTNPPPNFSC RYLTHSAEQI IWARKSHKHK HVFNYEILKK INNDKQMRDV
WSFPAIAPWE KVNGKHPTQK PLALLVRLLL MASDGNSLIG DPFSGSSTTG IAANLLKRKF
IGIEKESEFI KISINRKSEL DARYKEIRSK IKDLNLISPF FKPL
//
