ID   K2MBJ9_TRYCR            Unreviewed;       401 AA.
AC   K2MBJ9;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   22-FEB-2023, entry version 23.
DE   RecName: Full=NF-kappa-B-activating protein C-terminal domain-containing protein {ECO:0000259|Pfam:PF06047};
GN   ORFNames=MOQ_003607 {ECO:0000313|EMBL:EKF32533.1};
OS   Trypanosoma cruzi marinkellei.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX   NCBI_TaxID=85056 {ECO:0000313|EMBL:EKF32533.1, ECO:0000313|Proteomes:UP000007350};
RN   [1] {ECO:0000313|EMBL:EKF32533.1, ECO:0000313|Proteomes:UP000007350}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B7 {ECO:0000313|EMBL:EKF32533.1,
RC   ECO:0000313|Proteomes:UP000007350};
RX   PubMed=23035642; DOI=10.1186/1471-2164-13-531;
RA   Franzen O., Talavera-Lopez C., Ochaya S., Butler C.E., Messenger L.A.,
RA   Lewis M.D., Llewellyn M.S., Marinkelle C.J., Tyler K.M., Miles M.A.,
RA   Andersson B.;
RT   "Comparative genomic analysis of human infective Trypanosoma cruzi lineages
RT   with the bat-restricted subspecies T. cruzi marinkellei.";
RL   BMC Genomics 13:531-531(2012).
CC   -!- SIMILARITY: Belongs to the NKAP family.
CC       {ECO:0000256|ARBA:ARBA00009313}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKF32533.1}.
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DR   EMBL; AHKC01009781; EKF32533.1; -; Genomic_DNA.
DR   AlphaFoldDB; K2MBJ9; -.
DR   EnsemblProtists; EKF32533; EKF32533; MOQ_003607.
DR   OrthoDB; 2883730at2759; -.
DR   Proteomes; UP000007350; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   InterPro; IPR040466; NKAP.
DR   InterPro; IPR009269; NKAP_C.
DR   PANTHER; PTHR13087; NF-KAPPA B ACTIVATING PROTEIN; 1.
DR   PANTHER; PTHR13087:SF0; NKAP_C DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF06047; Nkap_C; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007350};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          310..393
FT                   /note="NF-kappa-B-activating protein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF06047"
FT   REGION          112..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          283..307
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   401 AA;  45385 MW;  8B09561707E68ADB CRC64;
     MVPLFLHFPQ KGLPFLFTLL FFFSFVVCVC VHLQQLKFEE ERVKRGKDVE KNKINNKNNR
     KYLQKGLMAT DSFWFPASEP TGEELETTIF LTFLQNIFST QNVSANREAA QMERKGNRLF
     HQKRKRNRHE DSAEAEQQER GGNLFHIISC IVHAAGIAYE PPLEEQGVAA SGVVSMPAET
     TTSTNTPQPE KDVSFQGDYA GPNKFVQQPR SALASLVESA RLKERLQKTG NSERKTRTFM
     AVSAVPLRSN NEDAKIMLER HKSPTASEQS GDDFGVALPH GSFISDGTNG PSKKFEAPVA
     KHPSQMSQEE FLRQFKRAPR RGEIGYDAES VAAAEAVGYV MSGTRNKEKQ HYVDNIQRKL
     HEKEARKLRL QFRKVEDERT DNTMIQAIIA MVNEKTPHEA L
//