ID   K2MNX2_TRYCR            Unreviewed;       330 AA.
AC   K2MNX2;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Trans-sialidase, putative {ECO:0000313|EMBL:EKF28815.1};
GN   ORFNames=MOQ_007424 {ECO:0000313|EMBL:EKF28815.1};
OS   Trypanosoma cruzi marinkellei.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX   NCBI_TaxID=85056 {ECO:0000313|EMBL:EKF28815.1, ECO:0000313|Proteomes:UP000007350};
RN   [1] {ECO:0000313|EMBL:EKF28815.1, ECO:0000313|Proteomes:UP000007350}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B7 {ECO:0000313|EMBL:EKF28815.1,
RC   ECO:0000313|Proteomes:UP000007350};
RX   PubMed=23035642; DOI=10.1186/1471-2164-13-531;
RA   Franzen O., Talavera-Lopez C., Ochaya S., Butler C.E., Messenger L.A.,
RA   Lewis M.D., Llewellyn M.S., Marinkelle C.J., Tyler K.M., Miles M.A.,
RA   Andersson B.;
RT   "Comparative genomic analysis of human infective Trypanosoma cruzi lineages
RT   with the bat-restricted subspecies T. cruzi marinkellei.";
RL   BMC Genomics 13:531-531(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKF28815.1}.
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DR   EMBL; AHKC01014826; EKF28815.1; -; Genomic_DNA.
DR   AlphaFoldDB; K2MNX2; -.
DR   EnsemblProtists; EKF28815; EKF28815; MOQ_007424.
DR   Proteomes; UP000007350; Unassembled WGS sequence.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13859; BNR_3; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007350};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           27..330
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003861420"
FT   DOMAIN          52..322
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13859"
FT   REGION          100..119
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          306..330
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   330 AA;  35700 MW;  23A1B0F180FC9030 CRC64;
     MSRHLLHSAL LLILLVVMCC NTAAEGEQST GPQFEWKDLK SESGVTVDSL GVPGLLKVGG
     HVFAVAEAQC KEAGVSFTGI ASQLINKDTA QQKMELLKDP KDNTQFLEGD GSEEPKKKVD
     LSRPTTIVEG NDIYMLVGKY SATAVSQVQN SGAADLGFLL VKGNVSDESG VVKGIHWKNN
     KDVSRVSFSE QTDLWTRLIG GGGSGIKTKN GTFVFPVEGT KKKTEGEAEE DEKAVSLILY
     SSDNNLWTLS KGMSDGGCSA PSVVEWKDNQ LMMMTACDDG RRRVYESGDK GESWTEALGT
     LSRVWGNKHE GPEKGVGSGF SHSDDCWRRR
//