ID K2N9B5_TRYCR Unreviewed; 888 AA.
AC K2N9B5;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Extracellular receptor, putative {ECO:0000313|EMBL:EKF31426.1};
GN ORFNames=MOQ_004739 {ECO:0000313|EMBL:EKF31426.1};
OS Trypanosoma cruzi marinkellei.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=85056 {ECO:0000313|EMBL:EKF31426.1, ECO:0000313|Proteomes:UP000007350};
RN [1] {ECO:0000313|EMBL:EKF31426.1, ECO:0000313|Proteomes:UP000007350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B7 {ECO:0000313|EMBL:EKF31426.1,
RC ECO:0000313|Proteomes:UP000007350};
RX PubMed=23035642; DOI=10.1186/1471-2164-13-531;
RA Franzen O., Talavera-Lopez C., Ochaya S., Butler C.E., Messenger L.A.,
RA Lewis M.D., Llewellyn M.S., Marinkelle C.J., Tyler K.M., Miles M.A.,
RA Andersson B.;
RT "Comparative genomic analysis of human infective Trypanosoma cruzi lineages
RT with the bat-restricted subspecies T. cruzi marinkellei.";
RL BMC Genomics 13:531-531(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKF31426.1}.
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DR EMBL; AHKC01010810; EKF31426.1; -; Genomic_DNA.
DR AlphaFoldDB; K2N9B5; -.
DR EnsemblProtists; EKF31426; EKF31426; MOQ_004739.
DR OrthoDB; 2970339at2759; -.
DR Proteomes; UP000007350; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060:SF134; G_PROTEIN_RECEP_F3_4 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 2.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:EKF31426.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007350};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..888
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003864346"
FT TRANSMEM 832..850
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 56..365
FT /note="Receptor ligand binding region"
FT /evidence="ECO:0000259|Pfam:PF01094"
FT DOMAIN 434..764
FT /note="Receptor ligand binding region"
FT /evidence="ECO:0000259|Pfam:PF01094"
SQ SEQUENCE 888 AA; 97746 MW; C3B3ABDAB9EA5593 CRC64;
MPPHSRCSIA VAVVCLLVLA EFVNSQQGPL RSAILIDLRQ TKMTNTSLQA AIDKYINDSV
NISKMFAQRP FIIDSNGSLL SALGQLEQLF FHEETFIDVL FLVETTDISV AVVDALRRSE
KTAGLTILSA HTSNPKLCDV ESNPNTVCVV PQDVVNLRGV LETVSSELAW YSVAVVFSSD
AYGTGVESVL ESQLSFARSA PTVVTKVFMK VSGTSDDDDD VIRKLLEYRP AGVLCFVKED
EFMRLRAAVV RLGKENELFL LGSREAINVL AFLEGSFQPL VKLWGALFVS QYTSVVNIVK
QGYFDIQQLD NYGAYVVSHL FDAMQAVTLA GNISSASIWS VHFDGFTGTV AFNAMTGQRE
GIIYSLLSKT YTTDQPLVTW NWKSSTSQPV ITNPNPSATG AIILPSPLRA VTVCLAAARS
CSEAEALNAM AYVFLRHNQK TSSTHGATSF IPLVINTGVS GVEGLVSLIP VARACSVLLG
PGRGLVALAL TPVVNQFALT QLDFNTAEGV FADRLAYPYF SRSTPKDAFN YLVFGDLCAY
FAWERVLILG LNDQFGNARL ESMQKSMRQR NIHLERTHMI ESMGKEQLVN AMEAIYKKDI
SRIVIVLLPL YGEEAKMFFE LFTELSYMKN YIFFLGKELC QYAASHPEER EKAQSSLCIF
PYVEPQRLEA INNESAQSGL YNNQVRILSQ GGFAAEATYC NLTTIRHGAA FAIDAAYAVI
DSVDRAVNAG VSLNLSANIM PFVRSTSIDG LTGNFTIDKA GNRDLASFGV DIQMINRTLY
LGMWSSKQQS PFRYTATEPI VWMTGSRETP ADTFRDIQFI LGTTVSASPG TIVLSVLGFV
GTIAVFAFCY RHYKLQKLVE LSLQSNRVPV TENEMRRLRG ARSFVSDL
//
