ID   K2RAG6_MACPH            Unreviewed;       417 AA.
AC   K2RAG6;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Cobalamin (Vitamin B12) biosynthesis CobW-like protein {ECO:0000313|EMBL:EKG09882.1};
GN   ORFNames=MPH_13089 {ECO:0000313|EMBL:EKG09882.1};
OS   Macrophomina phaseolina (strain MS6) (Charcoal rot fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetes incertae sedis; Botryosphaeriales; Botryosphaeriaceae;
OC   Macrophomina.
OX   NCBI_TaxID=1126212 {ECO:0000313|EMBL:EKG09882.1, ECO:0000313|Proteomes:UP000007129};
RN   [1] {ECO:0000313|EMBL:EKG09882.1, ECO:0000313|Proteomes:UP000007129}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MS6 {ECO:0000313|EMBL:EKG09882.1,
RC   ECO:0000313|Proteomes:UP000007129};
RX   PubMed=22992219; DOI=10.1186/1471-2164-13-493;
RA   Islam M.S., Haque M.S., Islam M.M., Emdad E.M., Halim A., Hossen Q.M.M.,
RA   Hossain M.Z., Ahmed B., Rahim S., Rahman M.S., Alam M.M., Hou S., Wan X.,
RA   Saito J.A., Alam M.;
RT   "Tools to kill: Genome of one of the most destructive plant pathogenic
RT   fungi Macrophomina phaseolina.";
RL   BMC Genomics 13:493-493(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKG09882.1}.
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DR   EMBL; AHHD01000564; EKG09882.1; -; Genomic_DNA.
DR   AlphaFoldDB; K2RAG6; -.
DR   STRING; 1126212.K2RAG6; -.
DR   VEuPathDB; FungiDB:MPH_13089; -.
DR   eggNOG; KOG2743; Eukaryota.
DR   HOGENOM; CLU_017452_2_1_1; -.
DR   InParanoid; K2RAG6; -.
DR   OrthoDB; 50694at2759; -.
DR   Proteomes; UP000007129; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR011629; CobW-like_C.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR43603; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR   PANTHER; PTHR43603:SF1; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR   Pfam; PF02492; cobW; 1.
DR   Pfam; PF07683; CobW_C; 1.
DR   SMART; SM00833; CobW_C; 1.
DR   SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007129}.
FT   DOMAIN          139..353
FT                   /note="CobW C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00833"
FT   REGION          169..246
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          398..417
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        191..228
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   417 AA;  47724 MW;  C22F8C6D9F598A09 CRC64;
     MVTVVDAFRF FAEFNTGEFL TDRFGRDEVP AEDERTISDL MADQIEFANV IVINKTDMVD
     RKTCERVRGC IKALNPKAKV VETKHSKVAA GDIVGTGLFK LEEAQMMSGW LASLQEMFIM
     DVNGKKRKAP KPETLEYGIN SFVYRARKPF DPMKLYRLLA GKFVLIQPDP YDEDEGEEGS
     DAQDDASDKG SSNAVDSDED EVMSDARSKP ATHEQSKRKD SKGEDLVGQE EGDENEEEDA
     FLKNLPTEPS AIVAAKAADP VWAKMHRSKG WLWFATRPQQ AGSWNTAGAM LRVEYEQDWY
     CELPEEEWAP DEEVKAAIQK DFVGEWGDRR QEIVFIGESL DEKKITQMLN SCLLTNKEFK
     KWEKLMRRKG VDLERKEEKL NEWWDDSYWA EWTVGEEHDH GHAEGNDHGH HNHGHKH
//