ID K2RBI4_MACPH Unreviewed; 795 AA.
AC K2RBI4;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=AB-hydrolase-associated lipase region {ECO:0000313|EMBL:EKG11918.1};
GN ORFNames=MPH_10962 {ECO:0000313|EMBL:EKG11918.1};
OS Macrophomina phaseolina (strain MS6) (Charcoal rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Botryosphaeriales; Botryosphaeriaceae;
OC Macrophomina.
OX NCBI_TaxID=1126212 {ECO:0000313|EMBL:EKG11918.1, ECO:0000313|Proteomes:UP000007129};
RN [1] {ECO:0000313|EMBL:EKG11918.1, ECO:0000313|Proteomes:UP000007129}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MS6 {ECO:0000313|EMBL:EKG11918.1,
RC ECO:0000313|Proteomes:UP000007129};
RX PubMed=22992219; DOI=10.1186/1471-2164-13-493;
RA Islam M.S., Haque M.S., Islam M.M., Emdad E.M., Halim A., Hossen Q.M.M.,
RA Hossain M.Z., Ahmed B., Rahim S., Rahman M.S., Alam M.M., Hou S., Wan X.,
RA Saito J.A., Alam M.;
RT "Tools to kill: Genome of one of the most destructive plant pathogenic
RT fungi Macrophomina phaseolina.";
RL BMC Genomics 13:493-493(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKG11918.1}.
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DR EMBL; AHHD01000465; EKG11918.1; -; Genomic_DNA.
DR AlphaFoldDB; K2RBI4; -.
DR STRING; 1126212.K2RBI4; -.
DR VEuPathDB; FungiDB:MPH_10962; -.
DR eggNOG; KOG2624; Eukaryota.
DR HOGENOM; CLU_024238_0_0_1; -.
DR InParanoid; K2RBI4; -.
DR OrthoDB; 5471104at2759; -.
DR Proteomes; UP000007129; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR006693; AB_hydrolase_lipase.
DR PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR PANTHER; PTHR11005:SF160; STEROL ESTERASE 1-RELATED; 1.
DR Pfam; PF04083; Abhydro_lipase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:EKG11918.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007129};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 169..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 270..359
FT /note="Partial AB-hydrolase lipase"
FT /evidence="ECO:0000259|Pfam:PF04083"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 88..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 576..645
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 747..795
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..112
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..612
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 613..639
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 747..769
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 776..795
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 795 AA; 90522 MW; EDE3AF1A4F3242A8 CRC64;
MPSKASAAPE KAKEKARSKA APAIEFSHQA ERLGQFTVEQ EDDQTGSTQA IEARFITPQD
PVIETANGGR LPAVPVDEAV KLNELKDVLD DRDPAESMPA ESRTREAKDG TIHGAAPNRA
SVSSQEADAP LREAIPVSKT NPLFPPLPVY GPPGLLRDLQ CFAFRVSSAI LSFAFLYVIM
LGSLFTSIPL LFQYLWRIIT FRDPNQYRPF YEEERRRKAA RREAEKAWMK QKSQDTATDA
RTPDSENFPG DNEEFVPTEG GPDPLVCDVG YYARRVGLDC ETFEVQTEDG FIIELWHLYN
PREYRPASTP RRAPHSPNIF HHDGKTNGTV DGYPFDKKKK YPVLMMHGLL QSSGAFCSND
DDSLAFFLAK SGYDVWLGNN RCGFNPRHSL LKYNDPRMWA WNIRQMGVMD LPALISRVLF
ETGFPKLALI AHSQGTTETF VALAKEQRPD LGDKISVFCA LAPAAYAGRL IGKMYFKFMR
IISPAMFRIM FGIHAFIPFM MHMHAILPGK FYGAMGYRIF SFLFNWTDER WEKDLRARLF
QFAPVYVSSE SMRWWLGREC FASQKCILQT RREKEMEERE DMEEEQNGKA GTEHRLREYY
NKQPRRGEYA SERSPSADSS SSSDNSDHQS ANGASSQARG ESRRNDRGRY AWYDSHAPPM
AFWVAGDDDL VDGGRLLRRF ERGREPCVDV VHSKIIEGYE HLDVIWAMDA IEKVGKEVRE
VIWRTAPEES KAVCRVPKDC ENVEPYKKHA HGIETREGER EEREHQANVG IDASPRNWRG
EEEDADKSDR RVATA
//
