ID K2RHV6_MACPH Unreviewed; 631 AA.
AC K2RHV6;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Cytochrome b5 {ECO:0000313|EMBL:EKG22171.1};
GN ORFNames=MPH_00499 {ECO:0000313|EMBL:EKG22171.1};
OS Macrophomina phaseolina (strain MS6) (Charcoal rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Botryosphaeriales; Botryosphaeriaceae;
OC Macrophomina.
OX NCBI_TaxID=1126212 {ECO:0000313|EMBL:EKG22171.1, ECO:0000313|Proteomes:UP000007129};
RN [1] {ECO:0000313|EMBL:EKG22171.1, ECO:0000313|Proteomes:UP000007129}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MS6 {ECO:0000313|EMBL:EKG22171.1,
RC ECO:0000313|Proteomes:UP000007129};
RX PubMed=22992219; DOI=10.1186/1471-2164-13-493;
RA Islam M.S., Haque M.S., Islam M.M., Emdad E.M., Halim A., Hossen Q.M.M.,
RA Hossain M.Z., Ahmed B., Rahim S., Rahman M.S., Alam M.M., Hou S., Wan X.,
RA Saito J.A., Alam M.;
RT "Tools to kill: Genome of one of the most destructive plant pathogenic
RT fungi Macrophomina phaseolina.";
RL BMC Genomics 13:493-493(2012).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKG22171.1}.
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DR EMBL; AHHD01000028; EKG22171.1; -; Genomic_DNA.
DR AlphaFoldDB; K2RHV6; -.
DR STRING; 1126212.K2RHV6; -.
DR VEuPathDB; FungiDB:MPH_00499; -.
DR eggNOG; KOG0537; Eukaryota.
DR eggNOG; KOG2404; Eukaryota.
DR HOGENOM; CLU_011398_4_5_1; -.
DR InParanoid; K2RHV6; -.
DR OrthoDB; 1605658at2759; -.
DR Proteomes; UP000007129; Unassembled WGS sequence.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR010960; Flavocytochrome_c.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR NCBIfam; TIGR01813; flavo_cyto_c; 1.
DR PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR PANTHER; PTHR43400:SF8; HYPOTHETICAL FUMARATE REDUCTASE (EUROFUNG); 1.
DR Pfam; PF00173; Cyt-b5; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR SMART; SM01117; Cyt-b5; 1.
DR SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR PROSITE; PS50255; CYTOCHROME_B5_2; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000007129}.
FT DOMAIN 547..623
FT /note="Cytochrome b5 heme-binding"
FT /evidence="ECO:0000259|PROSITE:PS50255"
FT REGION 492..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..532
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 631 AA; 68545 MW; 12678E2EE8FB7C59 CRC64;
MAPRVIVVGA GLSGLSAAHT IYLSGGNVVL LDKNNFMGGN STKATSGING ALTRTQVDHE
IRDSVKQFYD DTLKSARDKA RPDLIKVLTY KSAAAVEWLQ DVFNLDLTLV SRLGGHSQPR
THRGHDAKFP GMAITYALMQ RFEELAEKEP ERVQLIKKAK VTKVNKEGNR ATGVTYEFGG
EEVTLDGPVV LATGGYAADF SGDQSLLKQH RPDTYGLATT NGAHATGDGH KMLMAIGANG
IDMDKVQVHP TGLIDPKDPG SKWKFLAAEA LRGEGGLLLN SKGQRFSDEL GHRDYVSGKM
WEEKEKGLWP IRLVLNSKAS NVLDFHTRHY SGRGLMKKMT GKELAKEIGC GDKALQDTFQ
QYNRIAEGKE KDPFGKKFFH NLPFDINDTF HVALMEPVLH FTMGGIEIND QAQVLNKDGK
PFDGLFVCGE LAGGVHGANR LGGSSLLGCV VYGRVAGESA SKYLFQNLIS GGISNAAQRL
GQISLHIDPS QPGKVQVEWG SGASSGSDPV AQQKQQSAGP VLSGSADSSD PGKVSKPNDI
KSFTIPEKEF TLEEVKKHNK KDDLWIAVKG VVLDLTNWVD EHPGGPQALY SHMGKDASEE
FEMLHDDEVI PKYAPEVVIG RVKGQKITLE Y
//
