ID   K3VPM1_FUSPC            Unreviewed;       886 AA.
AC   K3VPM1;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=MHD domain-containing protein {ECO:0000259|PROSITE:PS51072};
GN   ORFNames=FPSE_03928 {ECO:0000313|EMBL:EKJ75748.1};
OS   Fusarium pseudograminearum (strain CS3096) (Wheat and barley crown-rot
OS   fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX   NCBI_TaxID=1028729 {ECO:0000313|EMBL:EKJ75748.1, ECO:0000313|Proteomes:UP000007978};
RN   [1] {ECO:0000313|EMBL:EKJ75748.1, ECO:0000313|Proteomes:UP000007978}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CS3096 {ECO:0000313|EMBL:EKJ75748.1,
RC   ECO:0000313|Proteomes:UP000007978};
RX   PubMed=23028337; DOI=10.1371/journal.ppat.1002952;
RA   Gardiner D.M., McDonald M.C., Covarelli L., Solomon P.S., Rusu A.G.,
RA   Marshall M., Kazan K., Chakraborty S., McDonald B.A., Manners J.M.;
RT   "Comparative pathogenomics reveals horizontally acquired novel virulence
RT   genes in fungi infecting cereal hosts.";
RL   PLoS Pathog. 8:E1002952-E1002952(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKJ75748.1}.
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DR   EMBL; AFNW01000081; EKJ75748.1; -; Genomic_DNA.
DR   RefSeq; XP_009255321.1; XM_009257046.1.
DR   AlphaFoldDB; K3VPM1; -.
DR   EnsemblFungi; EKJ75748; EKJ75748; FPSE_03928.
DR   GeneID; 20362546; -.
DR   KEGG; fpu:FPSE_03928; -.
DR   eggNOG; ENOG502QQAW; Eukaryota.
DR   HOGENOM; CLU_011037_0_0_1; -.
DR   OrthoDB; 2056337at2759; -.
DR   Proteomes; UP000007978; Chromosome 3.
DR   CDD; cd09264; AP_Syp1_MHD; 1.
DR   CDD; cd07650; F-BAR_Syp1p_like; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR001060; FCH_dom.
DR   InterPro; IPR028565; MHD.
DR   InterPro; IPR018808; Muniscin_C.
DR   InterPro; IPR049609; Syp1-like_MHD.
DR   PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR   PANTHER; PTHR23065:SF54; SUPPRESSOR OF YEAST PROFILIN DELETION; 1.
DR   Pfam; PF00611; FCH; 1.
DR   Pfam; PF10291; muHD; 1.
DR   SMART; SM00055; FCH; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   PROSITE; PS51072; MHD; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007978};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          613..886
FT                   /note="MHD"
FT                   /evidence="ECO:0000259|PROSITE:PS51072"
FT   REGION          240..317
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          329..489
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          583..613
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          829..866
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        243..299
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        346..375
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        397..431
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        843..857
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   886 AA;  95804 MW;  8FBD671788C60C91 CRC64;
     MEDMARAEYP AMLAALQPGQ AVQTLTERMK RMTRVNNEVA DWLQERRRVE DQYVQGLKKL
     TQFKVPNGQS ELGVFQAPWN RIIDSTESIA HAHHQLADRI EKDIEHPLRN FSNRKDFLNM
     NTMSNNLSTM AKDLDDSQNA VDKLTKKGGR ANTSKVESAT SKLESATGQW ESQAPFIFES
     LQALDESRVN NLRDLLTQYQ THESDSAQRV QENAMETLAL MLEINTEKEI ESFVHRATAG
     KAKLPTRNST RQSSFAGTTP STPVPPSTAD STNLPAQSAH TASPAPVTAP TSSHADDDMS
     ETSMPQEKPG GKLRRLGTMF GGRRRQSMHA GFGQLSPGKL GPSFGRLGTS HSQTDRGPSP
     RASSNNLQEH QRLSSLAETP DMPRVPDGEN DTPKPDAHEN TNGTSHNENL LDSPIPQSAG
     GTVNGNHEID LSNVQPPPGP PPSHKQDQPS APQNATKDSD GFNVPPPMND PISEAQREAK
     QESGEDPDQL LKVNIQQTPV EDEDPDAKMA ALSSVANSLK MGPATRRSGT VRGRRDVRHT
     MYVPPPNLPE SGTDSPISGL AASPILAPST SKGSALAALA SESSIAGTSD TQSVRSGNSL
     GGGNHPQHAH MTAPGLNSSI IESVSAVFED GVIKSASITG EVAFVNNPSD SGDAKTYETI
     RINNFAALER IGPNRIFVQN SSPDHHDQFN IDVSHLTKNA TAFSYRVFEE SEASVLAEHA
     PLLLKPAWKP QGDKLGLLLQ YQLNPASKIA APVSLHNVVI VAKYEGKSSG AQTKPVGIHL
     KDKHLVYWRI GDLTLTNDPQ KIVCRIIGSE GTEPKPGHIE ARWELTASGD QPVGSGISIS
     RLDEGKGKGK EISDDDPFAD DSASTEQKWV DVPVSRKLVS GKYEGR
//