ID K3XE76_SETIT Unreviewed; 958 AA.
AC K3XE76;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:RCV27228.1, ECO:0000313|EnsemblPlants:KQL06854};
GN Name=101769369 {ECO:0000313|EnsemblPlants:KQL06854};
GN ORFNames=SETIT_5G307900v2 {ECO:0000313|EMBL:RCV27228.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL06854, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EMBL:RCV27228.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL06854,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV27228.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV27228.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV27228.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQL06854}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL06854};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the RBOH (TC 5.B.1.3) family.
CC {ECO:0000256|ARBA:ARBA00007975}.
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DR EMBL; AGNK02003292; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003532; RCV27228.1; -; Genomic_DNA.
DR RefSeq; XP_004969859.1; XM_004969802.2.
DR AlphaFoldDB; K3XE76; -.
DR SMR; K3XE76; -.
DR STRING; 4555.K3XE76; -.
DR EnsemblPlants; KQL06854; KQL06854; SETIT_000193mg.
DR GeneID; 101769369; -.
DR Gramene; KQL06854; KQL06854; SETIT_000193mg.
DR KEGG; sita:101769369; -.
DR eggNOG; KOG0039; Eukaryota.
DR HOGENOM; CLU_005646_6_0_1; -.
DR InParanoid; K3XE76; -.
DR OMA; FEDNWKR; -.
DR OrthoDB; 367877at2759; -.
DR Proteomes; UP000004995; Chromosome V.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016174; F:NAD(P)H oxidase H2O2-forming activity; IBA:GO_Central.
DR GO; GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.
DR CDD; cd00051; EFh; 1.
DR CDD; cd06186; NOX_Duox_like_FAD_NADP; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR000778; Cyt_b245_heavy_chain.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR013112; FAD-bd_8.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR013130; Fe3_Rdtase_TM_dom.
DR InterPro; IPR013121; Fe_red_NAD-bd_6.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR013623; NADPH_Ox.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR11972; NADPH OXIDASE; 1.
DR PANTHER; PTHR11972:SF153; RESPIRATORY BURST OXIDASE HOMOLOG PROTEIN F; 1.
DR Pfam; PF08022; FAD_binding_8; 1.
DR Pfam; PF01794; Ferric_reduct; 1.
DR Pfam; PF08030; NAD_binding_6; 1.
DR Pfam; PF08414; NADPH_Ox; 1.
DR PRINTS; PR00466; GP91PHOX.
DR SFLD; SFLDS00052; Ferric_Reductase_Domain; 1.
DR SFLD; SFLDG01168; Ferric_reductase_subgroup_(FRE; 1.
DR SFLD; SFLDG01169; NADPH_oxidase_subgroup_(NOX); 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Peroxidase {ECO:0000256|ARBA:ARBA00022559};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 397..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 536..556
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 577..597
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 756..773
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 273..308
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 630..750
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 83..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 145..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..38
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..114
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..164
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 958 AA; 107746 MW; 749A951C979F4147 CRC64;
MRGGAAPAAG AGHHHQRWSG SAGTTPRSLS TGSSPRGSDR SSDDGEELVE VTLDLQEDDT
IILRSVEPAA AAAAAAAAAT GGAPRLPLGA RGDHAGGASS SSRSRSPSIR RTSSHRLLQF
SQELKAEAMS IARQFSQDLT KRFGRTHSRA EGQGHQQQPT SGIESALAAR AARRQRAQLD
RTRSGAHKAL RGLRFISSNK ANNAWMEVQA NFDRLACDGF LSRADFAECI GMTESKEFAL
ELFDTLSRRR QMQVDKINKE ELREIWQQIT DNSFDSRLQI FFDMVDKNAD GRIGEEEVKE
IIMLSASANK LSRLKEQAEE YAALIMEELD PEGLGYIELW QLETLLLQKD TYMNYSQALS
YTSQALSQNL AGLRKKSPIR KISTTLSYYL EDNWKRLWVL ALWIGIMAGL FTWKFMQYRN
RYVFNVMGYC VTTAKGAAET LKLNMAIILL PVCRNTITWL RNTRAAWALP FDDNINFHKT
IAAAIVVGII LHAGNHLVCD FPRLIKSSDE KYAPLGQYFG EIKPTYFTLV KGVEGITGLI
MVICMVIAFT LATRWFRRSL VKLPKPFDKL TGFNAFWYSH HLFIIVYLAL IVHGQWLYLI
HVWYRKTTWM YLAVPVCLYV GERVLRFFRS GSYSVRLLKV AIYPGNVLTL QMSKPPAFRY
KSGQYMFVQC PAVSPFEWHP FSITSAPGDD FLSIHVRQLG DWTRELKRVF AAACEPPVGG
KSGLLRADET TKKALPKLLI DGPYGSPAQD YSKYDVLLLV GLGIGATPFI SILKDLLNNI
IKMEEEEDAS TDLYPPVGPN KPHIDLGTLM TVTSKPKRVL RTTNAYFYWV TREQGSFDWF
KGVMNEIAEL DQRNIIEMHN YLTSVYEEGD ARSALITMLQ TLNHAKNGVD IVSGTKVRTH
FARPNWKKVL SKIASKHPYA KIGVFYCGAP VLAQELNKLC HEFNGKSTTK FEFHKEHF
//
