ID K3XEB6_SETIT Unreviewed; 912 AA.
AC K3XEB6;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL06660, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EnsemblPlants:KQL06660, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL06660,
RC ECO:0000313|Proteomes:UP000004995};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EnsemblPlants:KQL06660}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL06660};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
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DR EMBL; AGNK02003279; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K3XEB6; -.
DR EnsemblPlants; KQL06660; KQL06660; SETIT_000233mg.
DR Gramene; KQL06660; KQL06660; SETIT_000233mg.
DR eggNOG; KOG1187; Eukaryota.
DR HOGENOM; CLU_000288_24_0_1; -.
DR InParanoid; K3XEB6; -.
DR OMA; VAWACPF; -.
DR Proteomes; UP000004995; Chromosome V.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR47989:SF44; OS01G0709500 PROTEIN; 1.
DR PANTHER; PTHR47989; OS01G0750732 PROTEIN; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 537..813
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 95..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 879..912
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 246..260
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 565
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 912 AA; 97484 MW; 90F6F1D4DEB61383 CRC64;
MGRLGGGRGG GGGGLGSCGG GCALLAAALV VSALVIHGAG GLKQSHAPAV ARKVLLSITS
WHPQNNLDNA LHPSPVQDQR FERVGSAVST ETAVHPANHG KNHGIPVAAP SKGGHHHSMP
VNNTHGKTHG PPVVAPAKRK HHHAPANGEG PGISPSKSPI AHRNRHGNPV VAPPKEHSSH
LPSPNRSFRP APHKTNNASE PGHGNSGLHH SPAPAPVHLP PSKGRGQGNY AYAPHHPHQY
HSPSYSPGPA LPPVHPPETP VFKKPKALAP TPNQPLLSPP TNLYCTASCQ DPLTNSPPGT
TCLCVLPIKV ELRFGIALYT FFTLVAEFAQ DIASGVLMNQ SQVRVMGANA APDDPEKTIV
FIDLVPLEPK FDNTTALLVF ERFWHKKVII NPMHFGKYDV LYVQYEGLPP SPPASMNNGL
SNVNGQTFHP LAADVVNHGE RKGRGIIVII ILSSVFAFIL CAGAALVVYF KLRNHSHLTE
ASLVPTKPAG PGSAMAGNRL ESRPISASPS FSSSLVAYKG SAKAFSLVEM ERATQVFDES
RIIGEGGFGR VYEGILEDGE RVAIKVLKRD DQQGTREFLA EVEMLSRLHH RNLVKLIGIC
TEGHSRCLVY ELVPNGSVES HLHGSDKGAS RLDWDARLKI ALGAARALAY LHEDSSPRVI
HRDFKSSNIL LEHDFTPKVS DFGLARTALG EGNEHISTRV MGTFGYVAPE YAMTGHLLVK
SDVYSYGVVL LELLTGRKPV DMSRPPGQEN LVAWASSLLT SRDGLESIID PSLGSSIAFD
SIAKVAAIAS MCVQPEVDQR PFMGEVVQAL KLVCNEGSEF NGSTSFSQDL HIQDVEIMSR
ASMDMDVDPA LSAELFTSSA RYDAIDASGS FRRYSSSGPL RVGRAGHNKE RGLSTGSSSE
HVGLQRSRID SE
//
