ID K3XV68_SETIT Unreviewed; 890 AA.
AC K3XV68;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE RecName: Full=Sucrose-phosphate synthase {ECO:0000256|ARBA:ARBA00012536, ECO:0000256|RuleBase:RU368006};
DE EC=2.4.1.14 {ECO:0000256|ARBA:ARBA00012536, ECO:0000256|RuleBase:RU368006};
GN Name=101759319 {ECO:0000313|EnsemblPlants:KQL11251};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL11251, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EnsemblPlants:KQL11251, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL11251,
RC ECO:0000313|Proteomes:UP000004995};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EnsemblPlants:KQL11251}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL11251};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- FUNCTION: Plays a role in photosynthetic sucrose synthesis by
CC catalyzing the rate-limiting step of sucrose biosynthesis from UDP-
CC glucose and fructose- 6-phosphate. Involved in the regulation of carbon
CC partitioning in the leaves of plants. May regulate the synthesis of
CC sucrose and therefore play a major role as a limiting factor in the
CC export of photoassimilates out of the leaf. Plays a role for sucrose
CC availability that is essential for plant growth and fiber elongation.
CC {ECO:0000256|RuleBase:RU368006}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=beta-D-fructose 6-phosphate + UDP-alpha-D-glucose = H(+) +
CC sucrose 6(F)-phosphate + UDP; Xref=Rhea:RHEA:22172,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57634, ChEBI:CHEBI:57723,
CC ChEBI:CHEBI:58223, ChEBI:CHEBI:58885; EC=2.4.1.14;
CC Evidence={ECO:0000256|ARBA:ARBA00001481,
CC ECO:0000256|RuleBase:RU368006};
CC -!- PATHWAY: Glycan biosynthesis; sucrose biosynthesis; sucrose from D-
CC fructose 6-phosphate and UDP-alpha-D-glucose: step 1/2.
CC {ECO:0000256|ARBA:ARBA00005027, ECO:0000256|RuleBase:RU368006}.
CC -!- SUBUNIT: Homodimer or homotetramer. {ECO:0000256|ARBA:ARBA00011774,
CC ECO:0000256|RuleBase:RU368006}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC {ECO:0000256|ARBA:ARBA00006530, ECO:0000256|RuleBase:RU368006}.
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DR EMBL; AGNK02002587; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K3XV68; -.
DR EnsemblPlants; KQL11251; KQL11251; SETIT_005783mg.
DR Gramene; KQL11251; KQL11251; SETIT_005783mg.
DR HOGENOM; CLU_009583_24_0_1; -.
DR UniPathway; UPA00371; UER00545.
DR Proteomes; UP000004995; Chromosome IV.
DR ExpressionAtlas; K3XV68; baseline.
DR GO; GO:0016157; F:sucrose synthase activity; IEA:InterPro.
DR GO; GO:0046524; F:sucrose-phosphate synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005986; P:sucrose biosynthetic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR006380; SPP-like_dom.
DR InterPro; IPR012819; SPS_pln.
DR InterPro; IPR000368; Sucrose_synth.
DR NCBIfam; TIGR02468; sucrsPsyn_pln; 1.
DR PANTHER; PTHR46039; SUCROSE-PHOSPHATE SYNTHASE 3-RELATED; 1.
DR PANTHER; PTHR46039:SF4; SUCROSE-PHOSPHATE SYNTHASE 3-RELATED; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR Pfam; PF05116; S6PP; 1.
DR Pfam; PF00862; Sucrose_synth; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000256|RuleBase:RU368006};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU368006}.
FT DOMAIN 178..443
FT /note="Sucrose synthase"
FT /evidence="ECO:0000259|Pfam:PF00862"
FT DOMAIN 479..652
FT /note="Glycosyl transferase family 1"
FT /evidence="ECO:0000259|Pfam:PF00534"
FT DOMAIN 729..887
FT /note="Sucrose phosphatase-like"
FT /evidence="ECO:0000259|Pfam:PF05116"
FT REGION 117..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 890 AA; 99504 MW; E336C81D4327C5A7 CRC64;
MYGNDNWINS YLDAILDAGK GATGAGAGAA RGRGGGGGGG GGYGDRPSLL LRERGHFSPA
RYFVEEVITG YDETDLYKTW LRANAMRSPQ EKNTRLENMT WRIWNLARKK KEFEKEEANR
LSKRRLETEK QRNDATADMS EDLFEGVKGE DAGDPSVAYG DSTTGNTPKI SSFDKLYIVL
ISLHGLIRGE NMELGRDSDT GGQVKYVVEL AKALSSSPGV YRVDLLTRQI LAPNFDRGYG
ERDEMLASTS FKNLKCERGE NSGAHIVRIP FGPKDKHLAK ENIWPFIQEF VDGALGHVVR
MSKTIGEEIG SGCPVWPAVI HGHYASAGVA ATLLSGALNV PMVFTGHFLG KDKLEGLLKQ
GRQTREQINM TYKIMRRIEA EELSLDASEI VIASTRQEIE EQWNLYDGFE VMLARKLRAL
VKRGANCYGR YMPRMVIIPP GVEFGHMIND FDLYGDEDSP SPASEDPSIW FEIMRFFTNP
RKPMILAIAR PYAEKNITTL VKAFGECHAL RELANLTLIM GNREAISKMN KVSAAVLTSV
LTLIDEYDLY GQVAYPKHHK NSEVPDIYRL AARTKGAFVN VAYFEQFGVT LIEAAMHGLP
VIATKNGAPV EIHQVLDNGL LVDPHDQHSI ADALYKMLSE KQFWSRCREN GLKNIHQFSW
PEHCKNYLSR ILTLGPRHPA FGNKEEQKVP VNCRKHILVI AVDSVSKEDL VQIIRNSIEA
TRTGTLSGST GFVLSTSLTI AELRSLIKCT GMHPTDFDAF ICNSGSDIYY PSLPNNSHVT
FALDNNYRSH IEYRWGGEGL RKYLVKWASS VVERRGRTEK QVIFEDSEHS STYCLAFRVV
NPNHLPPLKE LQKLMRIQSL RCHALYNHGA TRLSVIPIHA SRSQALRSGA
//
