ID K3YG82_SETIT Unreviewed; 849 AA.
AC K3YG82;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Elongator complex protein 2 {ECO:0000256|ARBA:ARBA00020267};
GN Name=101779393 {ECO:0000313|EnsemblPlants:KQL02317};
GN ORFNames=SETIT_6G194600v2 {ECO:0000313|EMBL:RCV31645.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV31645.1};
RN [1] {ECO:0000313|EMBL:RCV31645.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL02317,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV31645.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV31645.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV31645.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQL02317}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL02317};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- PATHWAY: tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA
CC biosynthesis. {ECO:0000256|ARBA:ARBA00005043}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the WD repeat ELP2 family.
CC {ECO:0000256|ARBA:ARBA00005881}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGNK02003953; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003533; RCV31645.1; -; Genomic_DNA.
DR RefSeq; XP_004973786.1; XM_004973729.2.
DR AlphaFoldDB; K3YG82; -.
DR STRING; 4555.K3YG82; -.
DR EnsemblPlants; KQL02317; KQL02317; SETIT_013250mg.
DR GeneID; 101779393; -.
DR Gramene; KQL02317; KQL02317; SETIT_013250mg.
DR KEGG; sita:101779393; -.
DR eggNOG; KOG1063; Eukaryota.
DR HOGENOM; CLU_006430_2_0_1; -.
DR InParanoid; K3YG82; -.
DR OMA; ENFRHIS; -.
DR OrthoDB; 22040at2759; -.
DR Proteomes; UP000004995; Chromosome VI.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0033588; C:elongator holoenzyme complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0002098; P:tRNA wobble uridine modification; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 5.
DR InterPro; IPR037289; Elp2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44111; ELONGATOR COMPLEX PROTEIN 2; 1.
DR PANTHER; PTHR44111:SF1; ELONGATOR COMPLEX PROTEIN 2; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 12.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 228..277
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 647..688
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 695..736
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 849 AA; 92925 MW; E9066690CA1A208E CRC64;
MSPAAGELAG ARGEGGGMEV QRVFIGAGCN RVVNNVSWGA CGLVAFGAQN AVALFSPERG
EIVTTLPGHK APVNCTLWLP TKKDVLQVRG RETYYLLSGS ADGAIMAWKI GSGKGDWSHV
LQLPGMHKKG ITCLAGRMVS DTVAIFASTS SDSIVVIWEM VIEPTPGGSC KVSCLHTLSI
GSKPMVSLSL AVLPEQGSHL ILAMGGLDHK IHIYCGDKSG KFIKACELKG HSDWIRSLDF
SLPVMMSSGK HNLFLVSSSQ DRTIRIWKMD SEAVSSGSTA QLRKANIEMT SYIEGPLFVA
GNTSYQVSLE SLLVGHEDWV YSVEWQPPTL LPGDEAHQAM SILSASMDKM MMIWRPEKNT
GLWINSVTVG ELSHSALGFY GGHWQPDGKS ILAHGYGGSF HMWRDVGLDS ENWQPQIVPS
GHFAPVSDLT WARSGQYLLS VSHDQTTRIF APWRNQVKPG DMIYWREIAR PQIHGHDINC
VAFIQGSGNH RFVSGADEKV SRVFEAPLSF LKTLQQATLL KPDVSDDFDN VQVVGANMSA
LGLSQKPIYT HGVKESLSSN STDGPDSMET IPDAVPTVFT EPPVEDQLAW NTLWPESHKL
YGHGNELFSI CCDYEGKLVA SSCKAQSAPV AEIWLWEIGT WKAVGRLQSH NLTVTQMEFS
RDNVFLLSVS RDRHLSIFSI RKTKEGVEHH LVAKHEAHKR IVWACSWNPF GYEFATGSRD
KTVKIWCVQD ASSVKLLATL PQFRDSVTAL AWMGRDRASN AGILAVGMDN GLIELWGVSG
GRVSADSTPD SSPLSAACML RFDPLLCHVS TVHRLRWREP NSSDEKSALE LASCGADHCV
RVFDVHCRT
//
