ID K3Z3P6_SETIT Unreviewed; 890 AA.
AC K3Z3P6;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=E3 SUMO-protein ligase SIZ1 {ECO:0008006|Google:ProtNLM};
GN Name=101773204 {ECO:0000313|EnsemblPlants:KQL13150};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL13150, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EnsemblPlants:KQL13150, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL13150,
RC ECO:0000313|Proteomes:UP000004995};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EnsemblPlants:KQL13150}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL13150};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein sumoylation.
CC {ECO:0000256|ARBA:ARBA00004718}.
CC -!- SIMILARITY: Belongs to the PIAS family.
CC {ECO:0000256|ARBA:ARBA00005383}.
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DR EMBL; AGNK02001430; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K3Z3P6; -.
DR STRING; 4555.K3Z3P6; -.
DR EnsemblPlants; KQL13150; KQL13150; SETIT_021164mg.
DR Gramene; KQL13150; KQL13150; SETIT_021164mg.
DR eggNOG; KOG2169; Eukaryota.
DR InParanoid; K3Z3P6; -.
DR OMA; NSNEMHG; -.
DR UniPathway; UPA00886; -.
DR Proteomes; UP000004995; Chromosome III.
DR ExpressionAtlas; K3Z3P6; baseline.
DR GO; GO:0061665; F:SUMO ligase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016925; P:protein sumoylation; IBA:GO_Central.
DR CDD; cd15570; PHD_Bye1p_SIZ1_like; 1.
DR CDD; cd16792; SP-RING_Siz-like; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR InterPro; IPR031141; SIZ1/2_SP-RING.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR004181; Znf_MIZ.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10782:SF4; E3 SUMO-PROTEIN LIGASE SIZ1; 1.
DR PANTHER; PTHR10782; ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02037; SAP; 1.
DR Pfam; PF02891; zf-MIZ; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS50800; SAP; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS51044; ZF_SP_RING; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00452}.
FT DOMAIN 12..46
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT DOMAIN 354..435
FT /note="SP-RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51044"
FT REGION 466..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 469..483
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 489..503
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 527..555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 890 AA; 98787 MW; A6422CFF89557291 CRC64;
MADLASTCKD KLAYFRIKEL KDILNQLGLP KQGKKQDLVD RVLALLSDEQ GQRHLGWGRK
NALTREAVAK VVDDTYSRKM QVQCAPDLAS RSHSGSDFSH FRPKEEANDY YHVESKVRCL
CSSTMLNDNM IKCEDAKCQV WQHMTCVLIP DRPTEGVSPE VPPHFYCELC RLSRADPFWL
TIGNPLLPVK FMSSGVGNDG TSVSQSVEKT FQLSRSDRET IQRPEFELQV WCILINDKVQ
FRMQWPQYAE LQVNGIPVRV VTRPGSQLLG INGRDDGPLV TTCSLREGIN KISLSRVDTR
TFCFGVRIVR RRTIAQVLSL IPKEGEGESF MDALARVRRC LGGGGATDNA DSDSDLEVVT
ESVTVNLRCP NSGSRMRIAG RFKPCVHMGC FDLETFVELN QRSRKWQCPI CLKNYSIENL
MIDPYFNRIT SLLRNCSEDV NELDVKPDGS WRVKGDAATR ELSQWHMPDG TLCDSQEDTN
PGVESLNEFK REGTSDGHRS LKLGIKRNPN GIWQFSSKAD DKKPSVVGNH IQNNTGFPAP
NAMISSPTGS YKDGEDASVN QEGGGIQFDI SLNQEFDSFP RNFGQAYNTE DRQQQQQQQN
AADVIVLSDS DEENDAIVRP PAVYENTATN GNNFPFATNG AKSGYPERYQ EDAGVGTSGL
GLLSSNAGDF EINNWQMHSY PQPEQGFQFF GTDTDVANPF VASHNSFNIA PEDYSLDCNV
GIEEPSAAHD ISIIRNSNEM HGSLVGNPLA LAGDDPSLQI LFPSQPSTVP LQEELSERAN
APNGVHPDDW RISLTLAAGG GGNEESTSVD GLQSQPKVTS KEAGVEPLID AGLSPFFEFD
SFLFCYCFVP KDNGLLHFLF FLVARQPFSG SSWSTFQGRH LSFCSPKHEQ
//
