ID K3ZED9_SETIT Unreviewed; 1238 AA.
AC K3ZED9;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL17394, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EnsemblPlants:KQL17394, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL17394,
RC ECO:0000313|Proteomes:UP000004995};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EnsemblPlants:KQL17394}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL17394};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; AGNK02002150; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K3ZED9; -.
DR EnsemblPlants; KQL17394; KQL17394; SETIT_024933mg.
DR Gramene; KQL17394; KQL17394; SETIT_024933mg.
DR eggNOG; KOG4658; Eukaryota.
DR HOGENOM; CLU_000837_8_8_1; -.
DR InParanoid; K3ZED9; -.
DR OMA; GHHETIG; -.
DR Proteomes; UP000004995; Chromosome III.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1246; OS10G0130600 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995}.
FT DOMAIN 14..98
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 143..376
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 1238 AA; 139723 MW; B07C2AD89099DFFA CRC64;
MAELVGSMVV GPLLSLVKEK ASSYLLDQYK VMEGMEEQHE NLKVMLPAIL ERITDAEKQA
TYRQAIRPWL QKLKVAAYEA IQVFDEFNYE ALRRQAKKEG RYIKLGMGNR IMFRYRMGNK
LCKIVRDIEA LVKQMRDFRS RDEEKQKIVR MLVKEQANNK DPMVVPIVGM GGLGKTTLAQ
LIYNDPEVKK HFHQLLKWVC VSDDFDVCNL ANKICNASES NLENALQNLQ RELAGKRYLL
VLDDVWNKDA NKWNKLNACL KHGDVGSAIL TTTRDKEIAQ LMGTVEEHGI ARLDNKFIKE
IIEAKAFISQ ERKRADLAGL VDDVVDRCAG SPLAAKALGS VLRGKTTKEW EAVLSKSIAH
NKDDQILPIL KLSYDDLPSH MKQCFAFCAV FPKDHEIDVE RLIQLWMAND FIPEQKDGHH
ETIGKQIFSE LVSRSFFQDV KQVKGSRYGS VYWYFSTSTC KIHDLMHDVA LSVMGKEVAT
ITEKPKQSDE FLQNTCRHIL LSCKKPEAVL NDSLNIRSPA MQTLLCDEDI ESSLQHLAKY
SSLRALRLCQ IKSTILLKPK QLHLLRYLDI SGSDIVALPE DISILYNLQT LNVAYCQKLG
RLPKGIKYMT ALRHLYTHGC RELKRMPPEV GHLTSLQTLT NFVVGACPDC SSIAELQHLN
NLGGPLLLSQ LENVTKAADA KQANLGNKEE LRELSLNWTW TGSQEEKLHC HKVLEGLEAP
PGLEALRIED YQGTSFPTWM GTLTKMVELH VSNCNKSNKL PPLRSVPALQ VLRLKRLKKL
ESLCSGGTFF HFPNLKELTL DELPEFDRWC EVNWVQGEQI MFPQLEKLFI TNCGKVTALP
GPALLGGSCS GDYKEQDERK LWSAFPVLKV LELKCLAKFQ RWGGAAEATQ GQQIIFPQLE
GLSIEKCPEL AALPSATSQG VSFDHSDVTA WSAFPKLKKL LLEDLDSFKS LGMTEATHGD
QQIFPDLETL RVEKCPKLTT LPGLQDLKIE RINHALVYWP EKEFQSLVSL RRLTIDDCSG
LIGYAKAAPG QPISERNQVL PRLEDLDLWD CESLVEVFNV PASLKTMDLR GCPKLKSIFG
EQQDEPTFNQ GPSAAPKLSS SARDHLLLPC LESLYIYRCE SLSEVLNLPP SLREIDITRC
GKLQLLSGQL DGLQRLVIRI CPELRSLESC LGEFSTLEHL SLRECESLAS LPDGPQAYSS
LRHLQITSCP GIQSLPSSLK KRLDNIPEEY KYLDARYE
//
