ID K3ZEW1_SETIT Unreviewed; 590 AA.
AC K3ZEW1;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=Auxin efflux carrier component {ECO:0000256|RuleBase:RU362108};
GN ORFNames=SETIT_3G136000v2 {ECO:0000313|EMBL:RCV16414.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EMBL:RCV16414.1};
RN [1] {ECO:0000313|EMBL:RCV16414.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL14191,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV16414.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV16414.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV16414.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQL14191}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL14191};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- FUNCTION: May act as a component of the auxin efflux carrier.
CC {ECO:0000256|RuleBase:RU362108}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362108}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362108}.
CC -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69.1) family.
CC {ECO:0000256|ARBA:ARBA00009177, ECO:0000256|RuleBase:RU362108}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362108}.
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DR EMBL; AGNK02001533; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003530; RCV16414.1; -; Genomic_DNA.
DR AlphaFoldDB; K3ZEW1; -.
DR STRING; 4555.K3ZEW1; -.
DR EnsemblPlants; KQL14191; KQL14191; SETIT_025109mg.
DR Gramene; KQL14191; KQL14191; SETIT_025109mg.
DR eggNOG; ENOG502QRM7; Eukaryota.
DR HOGENOM; CLU_019285_1_1_1; -.
DR InParanoid; K3ZEW1; -.
DR OMA; YVMNLRF; -.
DR Proteomes; UP000004995; Chromosome III.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0010329; F:auxin efflux transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0010315; P:auxin export across the plasma membrane; IBA:GO_Central.
DR GO; GO:0009926; P:auxin polar transport; IBA:GO_Central.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-UniRule.
DR InterPro; IPR014024; Auxin_eff_plant.
DR InterPro; IPR004776; Mem_transp_PIN-like.
DR NCBIfam; TIGR00946; 2a69; 1.
DR PANTHER; PTHR31752; AUXIN EFFLUX CARRIER COMPONENT 1B-RELATED; 1.
DR PANTHER; PTHR31752:SF16; AUXIN EFFLUX CARRIER COMPONENT 3B-RELATED; 1.
DR Pfam; PF03547; Mem_trans; 1.
PE 3: Inferred from homology;
KW Auxin signaling pathway {ECO:0000256|ARBA:ARBA00023294,
KW ECO:0000256|RuleBase:RU362108};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362108};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362108};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362108}; Transport {ECO:0000256|RuleBase:RU362108}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 71..92
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 113..137
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 447..470
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 533..555
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 562..586
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT REGION 392..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 62347 MW; 93517855B77FE8E5 CRC64;
MISWHDLYTV LCAVVPLYVA MILAYGSVRW WGVLTPDQCS GINRFVAVFA VPLLSFHCIA
ASNPYVMNLR FVAADTLQKV IVLAALAVWS CLPARGGGGG GGATRAPPID WSITLFSLST
LPNTLIMGIP LLVAMYGRYS GDLLVQVVVL QCIVWYTLLL VLFEFRAARA LIAGQCPDTA
AAIADVRVDP DVVSLAGSQA EAQAEVAPDG RVRLVVRRST SVSRRSLATP RPSNLTGVEI
YSVSSSRNAT PRGSSFAYGD VSATGAAPPL HGASMRMSSF GAADLFSLHS SRQHTPRPSS
FDEHAVRARS AAAVAPSYDP KDMPTFEWSS GASAASEVSG LPVFRGGEHR AKDVRRLVPS
EAPPVGMSRA MRPGERVASF KAEAVQDALA KLESGSADQR QNVKDDGGEN GGGAGAGRAG
GQAPAGVMMR LILTMVWRRL IRNPNTYASV VGLTWSLISF RFHIAMPIIV RNSISILSDA
GLGMAMFSLG LFMAMQPKIV ACGNSVAAIT MAIRFLLGPA VMAATSAAVG LRGTLLCIAI
VQAALPQGIV PFVFAKEYDL HAAILCTGVI FGMLIGLPIA LVYYIILGLL
//
