ID K3ZF35_SETIT Unreviewed; 446 AA.
AC K3ZF35;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Peptidase A1 domain-containing protein {ECO:0000259|PROSITE:PS51767};
GN Name=101758222 {ECO:0000313|EnsemblPlants:KQL14388};
GN ORFNames=SETIT_3G151200v2 {ECO:0000313|EMBL:RCV16604.1};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL14388, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EMBL:RCV16604.1, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL14388,
RC ECO:0000313|Proteomes:UP000004995}, and Yugu1
RC {ECO:0000313|EMBL:RCV16604.1};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EMBL:RCV16604.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Yugu1 {ECO:0000313|EMBL:RCV16604.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQL14388}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL14388};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase A1 family.
CC {ECO:0000256|ARBA:ARBA00007447, ECO:0000256|RuleBase:RU000454}.
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DR EMBL; AGNK02001562; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM003530; RCV16604.1; -; Genomic_DNA.
DR RefSeq; XP_004961266.1; XM_004961209.1.
DR AlphaFoldDB; K3ZF35; -.
DR MEROPS; A01.A30; -.
DR EnsemblPlants; KQL14388; KQL14388; SETIT_025184mg.
DR GeneID; 101758222; -.
DR Gramene; KQL14388; KQL14388; SETIT_025184mg.
DR KEGG; sita:101758222; -.
DR eggNOG; KOG1339; Eukaryota.
DR HOGENOM; CLU_005738_8_0_1; -.
DR InParanoid; K3ZF35; -.
DR OMA; CSSTHDG; -.
DR OrthoDB; 469863at2759; -.
DR Proteomes; UP000004995; Chromosome III.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IBA:GO_Central.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd05476; pepsin_A_like_plant; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 2.
DR InterPro; IPR001461; Aspartic_peptidase_A1.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR034161; Pepsin-like_plant.
DR InterPro; IPR033121; PEPTIDASE_A1.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR032799; TAXi_C.
DR InterPro; IPR032861; TAXi_N.
DR PANTHER; PTHR47967:SF76; EUKARYOTIC ASPARTYL PROTEASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR47967; OS07G0603500 PROTEIN-RELATED; 1.
DR Pfam; PF14541; TAXi_C; 1.
DR Pfam; PF14543; TAXi_N; 1.
DR PRINTS; PR00792; PEPSIN.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 2.
DR PROSITE; PS51767; PEPTIDASE_A1; 1.
PE 3: Inferred from homology;
KW Aspartyl protease {ECO:0000256|ARBA:ARBA00022750,
KW ECO:0000256|RuleBase:RU000454}; Hydrolase {ECO:0000256|RuleBase:RU000454};
KW Protease {ECO:0000256|RuleBase:RU000454};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..446
FT /note="Peptidase A1 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010969153"
FT DOMAIN 90..439
FT /note="Peptidase A1"
FT /evidence="ECO:0000259|PROSITE:PS51767"
FT ACT_SITE 108
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
FT ACT_SITE 322
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
SQ SEQUENCE 446 AA; 46453 MW; CB53CBEBFCA8B08C CRC64;
MEWSGNLLAV LVLAAAAAVA SGKSARLELV PAAPVASVAQ RARDDRHRHA YISAKLASRR
GGSRRVAAEV GSSAASLPVS SGAYAGTGQY FVKFLVGTPA QEFTLVADTG SDLTWVKCHG
AGAATPGRVF CPKNSESWAP IPCSSNTCKL DVPFSLANCS APASPCSYDY RYKEASAGAR
GVVGTDSATI ALPGGNVAQL RDVVLGCSST HDGQSFQAAD GVLSLGNSKI SFASRAAARF
GGSFSYCLVD HLAPRDATGY LAFGPGGPAP RDAAPAAQTP LLLDPQMPFY GVKVEAIHVA
GKALAIPAEV WDASKNGGAI LDSGTTLTVL ASPAYKAVVA ALSAHLAGIP KVAFPPFEHC
YNWTARRPGA PEIPKLAVQF AGSARLEPPA KSYVIDVKPD VKCIGVQEGE WPGVSVIGNI
LQQEHLWEFD VKNRFVRFKQ STSCTR
//
