ID K3ZR64_SETIT Unreviewed; 699 AA.
AC K3ZR64;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=protein-serine/threonine phosphatase {ECO:0000256|ARBA:ARBA00013081};
DE EC=3.1.3.16 {ECO:0000256|ARBA:ARBA00013081};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL25999, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EnsemblPlants:KQL25999, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL25999,
RC ECO:0000313|Proteomes:UP000004995};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EnsemblPlants:KQL25999}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL25999};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:83421; EC=3.1.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001512};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:61977; EC=3.1.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001482};
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DR EMBL; AGNK02001271; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K3ZR64; -.
DR EnsemblPlants; KQL25999; KQL25999; SETIT_029094mg.
DR Gramene; KQL25999; KQL25999; SETIT_029094mg.
DR eggNOG; KOG0698; Eukaryota.
DR HOGENOM; CLU_394532_0_0_1; -.
DR InParanoid; K3ZR64; -.
DR Proteomes; UP000004995; Chromosome II.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR CDD; cd00143; PP2Cc; 1.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR036278; Sialidase_sf.
DR PANTHER; PTHR43752; BNR/ASP-BOX REPEAT FAMILY PROTEIN; 1.
DR PANTHER; PTHR43752:SF3; BNR_ASP-BOX REPEAT FAMILY PROTEIN; 1.
DR Pfam; PF13088; BNR_2; 1.
DR Pfam; PF00481; PP2C; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000004995}.
FT DOMAIN 432..698
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT REGION 65..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..537
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 699 AA; 76853 MW; 471A212C6DD03EA9 CRC64;
MAMPNICCSL SKQHKWKIAA CVMMFSVLLV AFDSPFRTLI SKYLSSIVPS SGSSHDTTLT
QENRNLSSER ATNLSNSKPG QQIEHGTHNM NTSSTNATSS WSIVKEEFTF PAAGRSFNNC
HASTIVEIEK DNFLVSYFGG SIEGAPDVKI WTQRYSDGYW HPPVVADEEN ATAMWNPVLF
QLPSRELLLF YKIGEHPQNW SGAMKRSLNG GMSWSEREQL PPGILGPIKN KPFLLDDGRL
LCGSSVESWN SWGAWLEVTD DAGWTWRKYG PIFVESEKLG VIQPVPYQTT NGTIRMLLRS
YQTIGRVCIA DSSDGGLTWG YARKTELPNP NSGIDGIKMK DGRVALAYNT ESRGILKVAV
SLDDGISWGE VLTLENTEGV EFSYPAVIQT MDELVHVTYT YNRTQIKAAQ AQAVRETGRG
KSRASSGSRK VTYGFHLVEG RMPHGMEDRH VAEFRQLDDG NEVGLFAVFD GHSGADVATY
LSEHLFDNIL NEPDLDFWTD PMESIRRAYH RTDQKVLKMK KSDDDGGGGE GRKGRRQRGG
STAVTVILIN GETLVVANVG DSRAVLRDAA GAARQLSVDH EPLRERSAVE SRGGFVTEIH
GDVPRVDAQL AMSRAFGDGA IKEHISSDPD VCIEDVGEGA ELVVLASDGL WKVMSNQEAV
DEAGREAAGD ARDAAVRLVD EAVRRGSKDD ISCIVVRLH
//
