ID K4DFY0_SOLLC Unreviewed; 481 AA.
AC K4DFY0;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Anaphase-promoting complex subunit 4-like WD40 domain-containing protein {ECO:0000259|Pfam:PF12894};
GN Name=101257937 {ECO:0000313|EnsemblPlants:Solyc12g056490.1.1};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081 {ECO:0000313|EnsemblPlants:Solyc12g056490.1.1};
RN [1] {ECO:0000313|EnsemblPlants:Solyc12g056490.1.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc12g056490.1.1};
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [2] {ECO:0000313|EnsemblPlants:Solyc12g056490.1.1}
RP IDENTIFICATION.
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc12g056490.1.1};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat CDC20/Fizzy family.
CC {ECO:0000256|ARBA:ARBA00006445}.
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DR RefSeq; XP_004252641.1; XM_004252593.3.
DR AlphaFoldDB; K4DFY0; -.
DR STRING; 4081.K4DFY0; -.
DR PaxDb; 4081-Solyc12g056490-1-1; -.
DR EnsemblPlants; Solyc12g056490.1.1; Solyc12g056490.1.1; Solyc12g056490.1.
DR GeneID; 101257937; -.
DR Gramene; Solyc12g056490.1.1; Solyc12g056490.1.1; Solyc12g056490.1.
DR KEGG; sly:101257937; -.
DR eggNOG; KOG0305; Eukaryota.
DR HOGENOM; CLU_014831_4_2_1; -.
DR InParanoid; K4DFY0; -.
DR OMA; WHASNGK; -.
DR OrthoDB; 762186at2759; -.
DR PhylomeDB; K4DFY0; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000004994; Chromosome 12.
DR GO; GO:0005680; C:anaphase-promoting complex; IBA:GO_Central.
DR GO; GO:0010997; F:anaphase-promoting complex binding; IBA:GO_Central.
DR GO; GO:1990757; F:ubiquitin ligase activator activity; IBA:GO_Central.
DR GO; GO:0031145; P:anaphase-promoting complex-dependent catabolic process; IBA:GO_Central.
DR GO; GO:1905786; P:positive regulation of anaphase-promoting complex-dependent catabolic process; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR033010; Cdc20/Fizzy.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19918:SF51; ANAPHASE-PROMOTING COMPLEX SUBUNIT 4 WD40 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR19918; CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000004994};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 195..267
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 211..252
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 294..335
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 424..457
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 462..481
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 481 AA; 53133 MW; 778D187672EDC256 CRC64;
MENPSSNSME PQTPFDPNSN MNPKTPSKTN LIPGFNSYHP SPSRSIYSDR FIPSRTSSNF
ALFGLPLSPK SSNTEDSNSG YTSLLRTALF GPDSGNVVNP VTPEKGVRGN GRNLKRPNCN
IFRYKTETRQ RLDSLLPYEF DDQMRGVSTS PVKVPRKVPK SPYKVLDAPA LQDDFYLNLV
DWSSQNVLAV GLGSSVYLWH ASNGKVVKLC DLENDDNVTS VGWAQRGTHL AVGTSNGKVQ
LWDASHGKMT RTMEGHRLRV GALSWSSSQL SSGSRDKSIL QRDIRAQDDY VSKLSGHKSE
VCGLKWSPDS RELASGGNDN RLFVWNNHST QPILKYCEHT AAVKAIAWSP HLHGLLASGG
GTADRCIRFW NTTTNTHLSC MDTGSQVCNL VWSKNANELV STHGYSQNQI ILWRYPTMTK
VATLTGHTYR VLYLAISPDG QMIVTGAGDE TLRFWNVFPS PKSQNTESEI GASSLGRTQI
R
//
