ID K4HGK8_ALLMI Unreviewed; 241 AA.
AC K4HGK8;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Inhibin beta A {ECO:0000313|EMBL:AFR13055.1};
DE Flags: Fragment;
GN Name=INHBA {ECO:0000313|EMBL:AFR13055.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:AFR13055.1};
RN [1] {ECO:0000313|EMBL:AFR13055.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=22993238; DOI=10.1098/rsbl.2012.0703;
RA Wiens J.J., Hutter C.R., Mulcahy D.G., Noonan B.P., Townsend T.M.,
RA Sites J.W.Jr., Reeder T.W.;
RT "Resolving the phylogeny of lizards and snakes (Squamata) with extensive
RT sampling of genes and species.";
RL Biol. Lett. 8:1043-1046(2012).
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; JN880632; AFR13055.1; -; Genomic_DNA.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF133; INHIBIN BETA A CHAIN; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 147..241
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT REGION 101..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFR13055.1"
FT NON_TER 241
FT /evidence="ECO:0000313|EMBL:AFR13055.1"
SQ SEQUENCE 241 AA; 27165 MW; FF518F2F71C355AF CRC64;
FLKVSKANRS RTKVTIRLYQ QHRQPKGNSE GAEEVEDVGL TGEKSETLIS EKAVDTRKST
WHIFPVSNSV QHLLDQGKSS LDVRISCDQC QETGASLVLM GKKKKKEDDG EGKEKEAGES
TGEEEKEQSH RPFLMXVARH SEDRQHRRRR RGLECDGKVN ICCKKQFFVS FKDIGWSDWI
IAPTGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM
S
//
